13,14-Dihydro PGE1-d4
13,14-Dihydro PGE1-d4 (13,14-Dihydroprostaglandin E1-d4) is deuterium labeled 13,14-Dihydro PGE1. 13,14-Dihydro PGE1 is a metabolite of PGE1 (Prostaglandin E1) which inhibits the ADP-induced platelet aggregation (ID50 = 10.8 ng/mL platelet rich plasma).
For research use only. We do not sell to patients.
- CAS No.: 2705226-66-8
- Formula: C20H32D4O5
- Molecular Weight:360.52
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Endogenous Metabolite Isoforms
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Biological Activity
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 2705226-66-8
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Unlabeled Cas 19313-28-1
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Molecular Weight 360.52
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Formula C20H32D4O5
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SMILES
CCCCC[C@@H](CC[C@@H]([C@@H](CC1=O)O)[C@H]1CCCC([2H])(C([2H])(CC(O)=O)[2H])[2H])O
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Synonyms
13,14-Dihydroprostaglandin E1-d4; PGE0-d4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Katzenschlager R, et al. Synergism between PGE1-metabolites(13,14-dihydro-prostaglandin E1, 15-keto prostaglandin E1, 15-keto-13,14-dihydro-prostaglandin E1) and nitric oxide (NO) on platelet aggregation. Prostaglandins Leukot Essent Fatty Acids. 1992 Mar;45(3):207-10. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)