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  3. 1H-1,2,4-Triazol-3-amine

1H-1,2,4-Triazol-3-amine consists of a triazole ring system and an amino group attached to carbon atom 3. The compound has potential applications in various fields such as medicinal chemistry, agrochemicals and material science. In medicinal chemistry, 1H-1,2,4-Triazol-3-amine is used as a starting material for the synthesis of pharmaceutical compounds such as antifungal agents, anticancer agents, and enzyme inhibitors associated with cardiovascular disease. In agrochemicals, it can be used as a raw material for the synthesis of herbicides, fungicides and insecticides. Furthermore, 1H-1,2,4-Triazol-3-amine is used as a ligand in coordination chemistry and as a precursor for the production of new functional materials such as polymers and metal-organic frameworks.

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1H-1,2,4-Triazol-3-amine Chemical Structure

1H-1,2,4-Triazol-3-amine Chemical Structure

CAS No. : 61-82-5

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Based on 1 publication(s) in Google Scholar

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Description

1H-1,2,4-Triazol-3-amine consists of a triazole ring system and an amino group attached to carbon atom 3. The compound has potential applications in various fields such as medicinal chemistry, agrochemicals and material science. In medicinal chemistry, 1H-1,2,4-Triazol-3-amine is used as a starting material for the synthesis of pharmaceutical compounds such as antifungal agents, anticancer agents, and enzyme inhibitors associated with cardiovascular disease. In agrochemicals, it can be used as a raw material for the synthesis of herbicides, fungicides and insecticides. Furthermore, 1H-1,2,4-Triazol-3-amine is used as a ligand in coordination chemistry and as a precursor for the production of new functional materials such as polymers and metal-organic frameworks.

In Vitro

1H-1,2,4-Triazol-3-amine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

84.08

Formula

C2H4N4

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

NC1=NNC=N1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (1189.34 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 11.8934 mL 59.4672 mL 118.9343 mL
5 mM 2.3787 mL 11.8934 mL 23.7869 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.89%

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 11.8934 mL 59.4672 mL 118.9343 mL 297.3359 mL
5 mM 2.3787 mL 11.8934 mL 23.7869 mL 59.4672 mL
10 mM 1.1893 mL 5.9467 mL 11.8934 mL 29.7336 mL
15 mM 0.7929 mL 3.9645 mL 7.9290 mL 19.8224 mL
20 mM 0.5947 mL 2.9734 mL 5.9467 mL 14.8668 mL
25 mM 0.4757 mL 2.3787 mL 4.7574 mL 11.8934 mL
30 mM 0.3964 mL 1.9822 mL 3.9645 mL 9.9112 mL
40 mM 0.2973 mL 1.4867 mL 2.9734 mL 7.4334 mL
50 mM 0.2379 mL 1.1893 mL 2.3787 mL 5.9467 mL
60 mM 0.1982 mL 0.9911 mL 1.9822 mL 4.9556 mL
80 mM 0.1487 mL 0.7433 mL 1.4867 mL 3.7167 mL
100 mM 0.1189 mL 0.5947 mL 1.1893 mL 2.9734 mL
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1H-1,2,4-Triazol-3-amine Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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1H-1,2,4-Triazol-3-amine
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