2,3’-Anhydrothymidine
2,3’-Anhydrothymidine; 2’-Deoxy-3’,2-anhydro-5-methyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
For research use only. We do not sell to patients.
- CAS No.: 15981-92-7
- Formula: C10H12N2O4
- Molecular Weight:224.21
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Cellular Effect
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HL-60 | IC50 |
>1 mM
Compound: 1
|
Inhibition of human promyelocytic leukemic cell (HL-60) by XXT-microculture tetrazolium assay
Inhibition of human promyelocytic leukemic cell (HL-60) by XXT-microculture tetrazolium assay
|
[PMID: 2033590] |
| HL-60 | IC50 |
>1 mM
Compound: 1
|
Inhibition of human promyelocytic leukemic cell (HL-60) trypan blue exclusion assay
Inhibition of human promyelocytic leukemic cell (HL-60) trypan blue exclusion assay
|
[PMID: 2033590] |
Chemical Information
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CAS No. 15981-92-7
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Molecular Weight 224.21
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Formula C10H12N2O4
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SMILES
O=C(N=C1O2)C(C)=CN1[C@@H]3O[C@H](CO)[C@H]2C3
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Synonyms
2’-Deoxy-3’,2-anhydro-5-methyluridine
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Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)