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Cat. No.: HY-134960

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2,3-Indolobetulonic acid

Name: 2,3-Indolobetulonic acid
Brand: MedChemExpress
SKU: HY-134960
Price: 122.00 USD
Availability: InStock
Rating: 5 (1 reviews)

2,3-Indolobetulonic acid (compound 2), a triterpenoid, is α-glucosidase inhibitor with an IC₅₀ of 1.8 µM.

For research use only. We do not sell to patients.

CAS No.: 905837-93-6
Formula: C₃₆H₄₉NO₂
Molecular Weight:527.78

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

2,3-Indolobetulonic acid Chemical Structure

CAS No.: 905837-93-6

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

2,3-Indolobetulonic acid (compound 2), a triterpenoid, is α-glucosidase inhibitor with an IC₅₀ of 1.8 µM^[1].

IC₅₀ & Target^[1]

Glucosidase

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	7.6 μg/mL Compound: 7	Cytotoxicity against human A549 cells after 72 hrs by MTT assay Cytotoxicity against human A549 cells after 72 hrs by MTT assay	[PMID: 18752941]
DU-145	IC₅₀	8.86 μg/mL Compound: 7	Cytotoxicity against human DU145 cells after 72 hrs by MTT assay Cytotoxicity against human DU145 cells after 72 hrs by MTT assay	[PMID: 18752941]
HBL-100	IC₅₀	10.3 μg/mL Compound: 7	Cytotoxicity against human HBL100 cells after 72 hrs by MTT assay Cytotoxicity against human HBL100 cells after 72 hrs by MTT assay	[PMID: 18752941]
K562	IC₅₀	10.05 μg/mL Compound: 7	Cytotoxicity against human K-562 cells after 72 hrs by MTT assay Cytotoxicity against human K-562 cells after 72 hrs by MTT assay	[PMID: 18752941]
MIA PaCa-2	IC₅₀	6.7 μg/mL Compound: 7	Cytotoxicity against human MIA PaCa2 cells after 72 hrs by MTT assay Cytotoxicity against human MIA PaCa2 cells after 72 hrs by MTT assay	[PMID: 18752941]
NIH3T3	IC₅₀	6.9 μg/mL Compound: 7	Cytotoxicity against mouse NIH3T3 cells after 72 hrs by MTT assay Cytotoxicity against mouse NIH3T3 cells after 72 hrs by MTT assay	[PMID: 18752941]
PA-1	IC₅₀	6.01 μg/mL Compound: 7	Cytotoxicity against human PA-1 cells after 72 hrs by MTT assay Cytotoxicity against human PA-1 cells after 72 hrs by MTT assay	[PMID: 18752941]
SW-620	IC₅₀	5.15 μg/mL Compound: 7	Cytotoxicity against human SW620 cells after 72 hrs by MTT assay Cytotoxicity against human SW620 cells after 72 hrs by MTT assay	[PMID: 18752941]

Chemical Information

CAS No. 905837-93-6
Molecular Weight 527.78
Formula C₃₆H₄₉NO₂
SMILES

OC([C@]12[C@@]([C@@H](CC2)C(C)=C)([H])[C@]3([H])[C@@](CC1)([C@]4([C@]([C@@]5([C@@](C(C)(C6=C(C7=CC=CC=C7N6)C5)C)([H])CC4)C)([H])CC3)C)C)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Khusnutdinova, Elmira F, et al. Synthesis and evaluation of 2,3-indolotriterpenoids as new α-glucosidase inhibitors. Med Chem Res 26, 2737-2742.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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2,3-Indolobetulonic acid

Oxamic acid sodium

Migalastat hydrochloride

D-Fructose-13C6

UDP-GalNAc disodium

1,4-Dideoxy-1,4-imino-D-arabinitol hydrochloride

3-Hydroxybutyric acid-d4 sodium

AZ-33

1,4-D-Gulonolactone

GAPDH-IN-1

4,6-O-Benzylidene-D-glucose

Thielavin A

D-Iditol

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Bioz

2,3-Indolobetulonic acid

Oxamic acid sodium

Migalastat hydrochloride

D-Fructose-13C6

UDP-GalNAc disodium

1,4-Dideoxy-1,4-imino-D-arabinitol hydrochloride

3-Hydroxybutyric acid-d4 sodium

AZ-33

1,4-D-Gulonolactone

GAPDH-IN-1

4,6-O-Benzylidene-D-glucose

Thielavin A

D-Iditol

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

2,3-Indolobetulonic acid Related Classifications

HY-134960 Related Classifications

Bioz