2-Methoxyphenyl dihydrouracil
Based on 1 Customer Validation
2-Methoxyphenyl dihydrouracil (Compound 13) is a CRBN ligand, and can be used for synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 95.11%
- CAS No.: 2377643-33-7
- Formula: C12H12N2O5
- Molecular Weight:264.23
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Biological Activity
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Cereblon |
Chemical Information
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CAS No. 2377643-33-7
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Appearance Solid
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Molecular Weight 264.23
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Formula C12H12N2O5
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Color White to off-white
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SMILES
O=C(O)C1=CC=C(OC)C(N(C(N2)=O)CCC2=O)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 33.33 mg/mL (126.14 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.7846 mL | 18.9229 mL | 37.8458 mL | 94.6145 mL |
| 5 mM | 0.7569 mL | 3.7846 mL | 7.5692 mL | 18.9229 mL | |
| 10 mM | 0.3785 mL | 1.8923 mL | 3.7846 mL | 9.4615 mL | |
| 15 mM | 0.2523 mL | 1.2615 mL | 2.5231 mL | 6.3076 mL | |
| 20 mM | 0.1892 mL | 0.9461 mL | 1.8923 mL | 4.7307 mL | |
| 25 mM | 0.1514 mL | 0.7569 mL | 1.5138 mL | 3.7846 mL | |
| 30 mM | 0.1262 mL | 0.6308 mL | 1.2615 mL | 3.1538 mL | |
| 40 mM | 0.0946 mL | 0.4731 mL | 0.9461 mL | 2.3654 mL | |
| 50 mM | 0.0757 mL | 0.3785 mL | 0.7569 mL | 1.8923 mL | |
| 60 mM | 0.0631 mL | 0.3154 mL | 0.6308 mL | 1.5769 mL | |
| 80 mM | 0.0473 mL | 0.2365 mL | 0.4731 mL | 1.1827 mL | |
| 100 mM | 0.0378 mL | 0.1892 mL | 0.3785 mL | 0.9461 mL |