2-MSP-5-HA-VA-PAB-Exatecan
Based on 1 Customer Validation
2-MSP-5-HA-Val-Cit-PAB-Exatecan (A-24) is a drug-linker conjugate for ADC. 2-MSP-5-HA-Val-Cit-PAB-Exatecan consists of Exatecan (HY-13631) and a linker. 2-MSP-5-HA-Val-Cit-PAB-Exatecan can be used for synthesis of ADCs.
For research use only. We do not sell to patients.
- Purity: 97.96%
- CAS No.: 2878440-72-1
- Formula: C51H53FN8O11S
- Molecular Weight:1005.08
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Storage:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Biological Activity
Chemical Information
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CAS No. 2878440-72-1
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Appearance Solid
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Molecular Weight 1005.08
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Formula C51H53FN8O11S
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Color White to light yellow
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SMILES
CS(C1=NC=C(C=N1)C#CCCCC(N[C@@H](C(C)C)C(N[C@@H](C)C(NC(C=C2)=CC=C2COC(N[C@@H]3C4=C5C(C(N6C5)=CC([C@](O)(C(OC7)=O)CC)=C7C6=O)=NC8=CC(F)=C(C)C(CC3)=C84)=O)=O)=O)=O)(=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvent & Solubility
DMSO : 100 mg/mL (99.49 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.9949 mL | 4.9747 mL | 9.9495 mL | 24.8736 mL |
| 5 mM | 0.1990 mL | 0.9949 mL | 1.9899 mL | 4.9747 mL | |
| 10 mM | 0.0995 mL | 0.4975 mL | 0.9949 mL | 2.4874 mL | |
| 15 mM | 0.0663 mL | 0.3316 mL | 0.6633 mL | 1.6582 mL | |
| 20 mM | 0.0497 mL | 0.2487 mL | 0.4975 mL | 1.2437 mL | |
| 25 mM | 0.0398 mL | 0.1990 mL | 0.3980 mL | 0.9949 mL | |
| 30 mM | 0.0332 mL | 0.1658 mL | 0.3316 mL | 0.8291 mL | |
| 40 mM | 0.0249 mL | 0.1244 mL | 0.2487 mL | 0.6218 mL | |
| 50 mM | 0.0199 mL | 0.0995 mL | 0.1990 mL | 0.4975 mL | |
| 60 mM | 0.0166 mL | 0.0829 mL | 0.1658 mL | 0.4146 mL | |
| 80 mM | 0.0124 mL | 0.0622 mL | 0.1244 mL | 0.3109 mL |