2'-Deoxypseudoisocytidine
2'-Deoxypseudoisocytidine is a nucleoside analogue.
For research use only. We do not sell to patients.
- CAS No.: 65358-18-1
- Formula: C9H13N3O4
- Molecular Weight:227.22
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
In Vitro
2'-Deoxypseudoisocytidine is a modified base which can be used as a allele-specific blocker probe to discriminate sequence variation between different alleles and quantitate rare (e.g., mutant) allelic variants, such as SNPs, or nucleotide (NT) insertions or deletions, in samples comprising abundant allelic variants with high specificity and selectivity[1]. 2'-Deoxypseudoisocytidine (2′d‐PIC) and its analogues are also used as novel base-pairing agents in oligonucleotides to investigate DNA and RNA structures and functions[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 65358-18-1
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Molecular Weight 227.22
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Formula C9H13N3O4
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SMILES
NC(NC1=O)=NC=C1[C@H]2C[C@H](O)[C@@H](CO)O2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
In Vitro:
DMSO : ≥ 106.5 mg/mL (468.71 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
References
Complete Stock Solution Preparation Table
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.4010 mL | 22.0051 mL | 44.0102 mL | 110.0255 mL |
| 5 mM | 0.8802 mL | 4.4010 mL | 8.8020 mL | 22.0051 mL | |
| 10 mM | 0.4401 mL | 2.2005 mL | 4.4010 mL | 11.0026 mL | |
| 15 mM | 0.2934 mL | 1.4670 mL | 2.9340 mL | 7.3350 mL | |
| 20 mM | 0.2201 mL | 1.1003 mL | 2.2005 mL | 5.5013 mL | |
| 25 mM | 0.1760 mL | 0.8802 mL | 1.7604 mL | 4.4010 mL | |
| 30 mM | 0.1467 mL | 0.7335 mL | 1.4670 mL | 3.6675 mL | |
| 40 mM | 0.1100 mL | 0.5501 mL | 1.1003 mL | 2.7506 mL | |
| 50 mM | 0.0880 mL | 0.4401 mL | 0.8802 mL | 2.2005 mL | |
| 60 mM | 0.0734 mL | 0.3668 mL | 0.7335 mL | 1.8338 mL | |
| 80 mM | 0.0550 mL | 0.2751 mL | 0.5501 mL | 1.3753 mL | |
| 100 mM | 0.0440 mL | 0.2201 mL | 0.4401 mL | 1.1003 mL |