3-(5-Bromo-2-chlorophenyl)piperidine-2,6-dione
3-(5-Bromo-2-chlorophenyl)piperidine-2,6-dione is a CRBN-type E3 ubiquitin ligase ligand that can be used to prepare PROTAC.
For research use only. We do not sell to patients.
- CAS No.: 2990057-63-9
- Formula: C11H9BrClNO2
- Molecular Weight:302.55
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
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Cereblon |
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2990057-63-9
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Molecular Weight 302.55
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Formula C11H9BrClNO2
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SMILES
O=C(C(C1=CC(Br)=CC=C1Cl)CC2)NC2=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
3-(5-Bromo-2-chlorophenyl)piperidine-2,6-dione Related Classifications
HY-W1111714 Related Classifications
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