3-Acetyl-beta-boswellic acid
Based on 2 publication(s) in Google Scholar
3-Acetyl-beta-boswellic acid is a boswellic acid isolated from Boswellia serrata gum resin.
For research use only. We do not sell to patients.
- Purity: 98.10%
- CAS No.: 5968-70-7
- Formula: C32H50O4
- Molecular Weight:498.74
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Publications Citing Use of MedChemExpress (MCE) 3-Acetyl-beta-boswellic acid
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
3 μM
Compound: 3
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Inhibition of microsomal PGES1 isolated from IL-1beta-stimulated human A549 cells preincubated for 15 mins followed by substrate addition measured after 1 min by RP-HPLC analysis
Inhibition of microsomal PGES1 isolated from IL-1beta-stimulated human A549 cells preincubated for 15 mins followed by substrate addition measured after 1 min by RP-HPLC analysis
|
[PMID: 24844534] |
| HeLa | IC50 |
22 μM
Compound: 3, ABA
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Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
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[PMID: 21334793] |
| HL-60 | IC50 |
10 μM
Compound: 3, ABA
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Cytotoxicity against human HL60 cells after 48 hrs by MTT assay
Cytotoxicity against human HL60 cells after 48 hrs by MTT assay
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[PMID: 21334793] |
| HUVEC | IC50 |
>100 μM
Compound: 2, ABA
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Antiproliferation activity against HUVEC cells after 48 hrs by CCK-8 assay
Antiproliferation activity against HUVEC cells after 48 hrs by CCK-8 assay
|
[PMID: 25819335] |
| Sf21 | IC50 |
>40 μM
Compound: 28
|
Inhibition of human recombinant COX2 expressed in baculovirus infected sf21 cells assessed as decrease in PGE2 formation using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition measured after 45 mins by LC-MS analysis
Inhibition of human recombinant COX2 expressed in baculovirus infected sf21 cells assessed as decrease in PGE2 formation using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition measured after 45 mins by LC-MS analysis
|
[PMID: 31774676] |
Chemical Information
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CAS No. 5968-70-7
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Appearance Solid
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Molecular Weight 498.74
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Formula C32H50O4
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Color White to off-white
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SMILES
C[C@@]([C@@]12C)(CC[C@@]3([H])[C@@]4(C)C(O)=O)[C@@](CC=C1[C@@]([C@H]5C)([H])[C@](C)(CC[C@H]5C)CC2)([H])[C@]3(CC[C@H]4OC(C)=O)C
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Publications (2)
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Journal Impact Factor
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Most Recent
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Phytomedicine
Xihuang Pill ameliorates the immune microenvironment of TNBC by activation of AMPKα-ACC signaling-mediated lipid metabolic reprogramming. [Abstract]2026 Jul 25:157:158311. PMID: 42172981 -
J Immunol
SZB120 Exhibits Immunomodulatory Effects by Targeting eIF2α to Suppress Th17 Cell Differentiation. [Abstract]2021 Mar 1;206(5):953-962. PMID: 33483349
Solvent & Solubility
DMSO : 100 mg/mL (200.51 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.0051 mL | 10.0253 mL | 20.0505 mL | 50.1263 mL |
| 5 mM | 0.4010 mL | 2.0051 mL | 4.0101 mL | 10.0253 mL | |
| 10 mM | 0.2005 mL | 1.0025 mL | 2.0051 mL | 5.0126 mL | |
| 15 mM | 0.1337 mL | 0.6684 mL | 1.3367 mL | 3.3418 mL | |
| 20 mM | 0.1003 mL | 0.5013 mL | 1.0025 mL | 2.5063 mL | |
| 25 mM | 0.0802 mL | 0.4010 mL | 0.8020 mL | 2.0051 mL | |
| 30 mM | 0.0668 mL | 0.3342 mL | 0.6684 mL | 1.6709 mL | |
| 40 mM | 0.0501 mL | 0.2506 mL | 0.5013 mL | 1.2532 mL | |
| 50 mM | 0.0401 mL | 0.2005 mL | 0.4010 mL | 1.0025 mL | |
| 60 mM | 0.0334 mL | 0.1671 mL | 0.3342 mL | 0.8354 mL | |
| 80 mM | 0.0251 mL | 0.1253 mL | 0.2506 mL | 0.6266 mL | |
| 100 mM | 0.0201 mL | 0.1003 mL | 0.2005 mL | 0.5013 mL |