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Cat. No.: HY-162546

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3-Hydroxypropanoic acid-pip-hydroquinone-dihydrouracil

3-hydroxypropanoic acid-pip-hydroquinone-dihydrouracil is a conjugate of E3 ligase ligand and linker that serve as a key intermediate for the synthesis of complete PROTAC HPK1 Degrader-2 (HY-162544).

For research use only. We do not sell to patients.

Formula: C₁₇H₂₂N₄O₄
Molecular Weight:346.38

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

3-Hydroxypropanoic acid-pip-hydroquinone-dihydrouracil Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

All E3 Ligase Ligand-Linker Conjugates Isoforms :

Chemical Information

Molecular Weight 346.38
Formula C₁₇H₂₂N₄O₄
SMILES

O=C(N1CCN(C2=CC=C(N3C(NC(CC3)=O)=O)C=C2)CC1)CCO
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. BeiGene, Ltd. Preparation of pyrrolo[2,3-b]pyrazine-based bifunctional compounds as HPK1 degraders and the use thereof. World Intellectual Property Organization, WO2023006063 A1 2023-02-02

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Keywords

3-Hydroxypropanoic acid-pip-hydroquinone-dihydrouracil

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Biological Activity
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Chemical Information
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References

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3-Hydroxypropanoic acid-pip-hydroquinone-dihydrouracil

All E3 Ligase Ligand-Linker Conjugates Isoforms

Biological Activity

Description

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

3-Hydroxypropanoic acid-pip-hydroquinone-dihydrouracil Related Classifications

HY-162546 Related Classifications

Bioz

Keywords

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