2. PROTAC
  3. Ligands for E3 Ligase
  4. 5-Br-6-F-Desamino lenalidomide

5-Br-6-F-Desamino lenalidomide is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. 5-Br-6-F-Desamino lenalidomide can be linked to a target protein ligand via a linker to form a PROTAC.

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5-Br-6-F-Desamino lenalidomide

5-Br-6-F-Desamino lenalidomide Estructura química

No. CAS : 2409005-96-3

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5-Br-6-F-Desamino lenalidomide Related Antibodies

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von Hippel-Lindau (VHL) MDM2 Cereblon IAP KLHDC2 Fbxo3 RNF4 DCAF11 DCAF1 UHRF1 TRIM21 NEURL1B

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Descripciòn

5-Br-6-F-Desamino lenalidomide is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. 5-Br-6-F-Desamino lenalidomide can be linked to a target protein ligand via a linker to form a PROTAC.

IC50 & Target

Cereblon

 

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

5-Br-6-F-Desamino lenalidomide Related Antibodies
Peso molecular

341.14

Fòrmula

C13H10BrFN2O3
No. CAS
Appearance

Solid

SMILES

O=C1NC(=O)C(N2C(=O)C3=CC(F)=C(Br)C=C3C2)CC1
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Pureza y Documentación
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5-Br-6-F-Desamino lenalidomide Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

5-Br-6-F-Desamino lenalidomide2409005-96-3Ligands for E3 LigaseE3 ligase-recruiting MoietyInhibitorinhibitorinhibit

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Nombre del producto:
5-Br-6-F-Desamino lenalidomide
Cat. No.:
HY-W243100
Cantidad:
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