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Cat. No.: HY-N15081

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5-N-Acetylardeemin

5-N-Acetylardeemin potentiated the cytotoxicity of the anticancer agent Vinblastine (HY-13780) in multidrug resistant human tumor cells.

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CAS No.: 148441-26-3
Formule: C₂₈H₂₈N₄O₃
Masse moléculaire:468.55

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (275 KB)

5-N-Acetylardeemin Chemical Structure

CAS No.: 148441-26-3

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- Cellular Effect
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

5-N-Acetylardeemin potentiated the cytotoxicity of the anticancer agent Vinblastine (HY-13780) in multidrug resistant human tumor cells^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
KB	IC₅₀	106.7 μM Compound: 24	Cytotoxicity against human KB cells assessed as cell growth inhibition Cytotoxicity against human KB cells assessed as cell growth inhibition	[PMID: 36375335]

Chemical Information

CAS No. 148441-26-3
Masse moléculaire 468.55
Formule C₂₈H₂₈N₄O₃
SMILES

C=CC(C)([C@]12[C@](N(C3=CC=CC=C32)C(C)=O)([H])N4[C@@](C(N5[C@@H](C4=O)C)=NC6=CC=CC=C6C5=O)([H])C1)C
Structure Classification
- Others
Initial Source
- Microorganisms
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (275 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Daigo Hayashi, et al. Synthesis and ABCG2 inhibitory evaluation of 5-N-acetylardeemin derivatives. Bioorg Med Chem. 2015 May 1;23(9):2010-23. [Content Brief]

Calculators

Calculateur de molarité

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Calculateur de dilution

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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