Tylophora ovata (Lindl.) Hook. ex Steud.

Ilexosapogenin A is a triterpenoid natural product aglycone. Ilexosapogenin A can be obtained from crataeguside via enzymatic hydrolysis or alkaline hydrolysis. Ilexosapogenin A can be used in studies on triterpenoid natural products, structural identification of triterpenoid glycosides, and glycoside hydrolysis.

Tylogenin is a Na⁺/K⁺ ATPase inhibitor with an IC₅₀ of 93.3 μM against rabbit-derived targets. Tylogenin inhibits antigen-induced mediator release from rabbit basophils and IgE-dependent histamine release from human leukocytes. Tylogenin exhibits antiallergic activity. Tylogenin can be used in research related to allergic diseases.

Tylophoridicine F is a cytotoxic agent. Tylophoridicine F can be isolated from T. atrofolliculata. Tylophoridicine F exhibits more cytotoxic activity on cells compared to Adriamycin (assessed using ileocecal adenocarcinoma cells and keratin-forming tumor cells).

Tylophorinicine is an anti-leukemic and anti-fungal agent. Tylophorinicine exhibits minimum inhibitory concentrations (MIC) in the range of 2-4 mg/mL for TdnH and 0.6-2.5 mg/mL for TnnH against Candida species. Tylophorinicine is a phenanthroindolizidine alkaloid from tylophora asthamatica and pergulatia pallid. Tylophorinicine inhibits thymidylate synthase by pergularinine.

Huazhongilexol is a cyano compound found in ilex centrochinensis.

Tylophorinidine is a natural phenanthroindolizidine alkaloid present in Tylophora ovata, and exhibits NFκB inhibitory activity. Tylophorinidine suppresses the cell viability of 3D co-culture spheroids derived from triple-negative breast cancer cells. Tylophorinidine is used in related research on triple-negative breast cancer.