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Cat. No.: HY-N17419

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Tylophoridicine F

Tylophoridicine F is a cytotoxic agent. Tylophoridicine F can be isolated from T. atrofolliculata. Tylophoridicine F exhibits more cytotoxic activity on cells compared to Adriamycin (assessed using ileocecal adenocarcinoma cells and keratin-forming tumor cells).

For research use only. We do not sell to patients.

CAS No.: 790234-59-2
Formula: C₂₃H₂₅NO₅
Molecular Weight:395.45

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

Tylophoridicine F Chemical Structure

CAS No.: 790234-59-2

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

Cellular Effect

Cell Line	Type	Value	Description	References
HepG2	GI₅₀	71 nM Compound: PA-4	Cytotoxicity against HepG2 cells Cytotoxicity against HepG2 cells	[PMID: 17531481]

In Vitro

Tylophoridicine F exhibits more cytotoxic activity on cells compared to Adriamycin (assessed using HCT-8 cells and HeLa (KB) cells)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 790234-59-2
Molecular Weight 395.45
Formula C₂₃H₂₅NO₅
SMILES

O[C@@H]1C2=C(C=CC(OC)=C3)C3=C(C=C(C(OC)=C4)OC)C4=C2C[N+]5([O-])[C@@]1([H])CCC5
Structure Classification
- Alkaloids
- Other Alkaloids
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Chandrika M, et al. An insight into the traditional uses, phytoconstituents and pharmacological activities of the genus Tylophora. Research Journal of Pharmacognosy, 2024, 11(1): 71-108.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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