Others

Nikkomycin J is an active compound. Nikkomycin J can be used for various researches.

Tyropeptin A-4 (TP-101) is a potent proteasome inhibitor with the ability to inhibit mammalian 20S proteasome activity. Tyropeptin A-4 exerts its inhibitory effect by binding to the site responsible for trypsin-like activity. Tyropeptin A-4 derivative TP-104 has a 20-fold increase in inhibitory activity over Tyropeptin A. TP-110 specifically inhibits trypsin-like activity without affecting PGPH and trypsin-like activity.

HI-253 is a non-nucleoside inhibitor of HIV-1 reverse transcriptase that has demonstrated greater activity than multiple anti-HIV compounds against both resistant and sensitive HIV-1 strains.

Tetrazine-Ph-PEG17-NHS ester is a PEG derivative composed of NHS ester, which can be conjugated to amino acids or other molecules containing amino groups.

Lab 170250F is an active compound.

(Rac)-Methylindazone ((Rac)-IAA-94) is the racemate of Methylindazone. Methylindazone is a potent CLIC1 channel blocker.

Lipid Y is a potent monosaccharide which contains two bromines per chain. lipid Y binds to a tryptophan residue in a membrane protein and then quenches the fluorescence of the tryptophan residue.

ThioD is a protein linker with a hydrophobic thioester.

SP-Chymostatin B (α-MAPI) is a strong inhibitor of many proteases, including chymotrypsin, papain, chymotrypsin-like serine proteinases, chymases, and lysosomal cysteine proteinases such as cathepsins A,B,C, H, and L. SP-Chymostatin B weakly inhibits human leucocyte elastase.

Leu-thiorphan is an active compound.

Silperisone hydrochloride is an organosilicone compound similar to tolperisone that has centrally acting muscle relaxant properties. Silperisone (hydrochloride) is a sodium channel protein type 2 alpha channel blocker that blocks sodium and calcium channels in cells, reduces muscle cell excitability and contraction, reduces peripheral tone, and acts as a muscle relaxant and peripheral vascular dilator. Silperisone (hydrochloride) is used to study recurrent painful myoclonus due to spinal cord injury, abnormal hypertonia due to cerebrovascular disease, myotonia symptoms, pyramidal tonia syndrome, multiple sclerosis myospasm, and myelitis.

N-Butylfluorescein is an alkyl-substituted fluorescein, can be used for synthesis of fluorogenic substrates for assaying phosphatidylinositol-specific phospholipase C.

H-0104 dihydrochloride is a ROCK inhibitor with significant intraocular pressure (IOP)-lowering activity. H-0104 dihydrochloride effectively reduces IOP when administered to monkey eyes. There may not be a direct relationship between the Iop-lowering effect of H-0104 dihydrochloride and ROCK inhibition.

Maltoheptaose hydrate is the hydrate form of Maltoheptaose (HY-127018). Maltoheptaose hydrate is a linear oligosaccharide composed of seven glucose units and belongs to the class of malto-oligosaccharides.

8-Hydroxy loxapine-d₈ is the deuterium labeled 8-Hydroxy loxapine (HY-127025). 8-Hydroxy loxapine is the relatively inactive oxidative metabolite of Loxapine (HY-17390), compared to 7-OH-loxapine.

Zatosetron is an active compound.

Tocamphyl is an active compound.

6,7-Epoxy-latrunculin A can be isolated from the Red Sea sponge Negombata magnifica and is initially identified as an inhibitor of actin polymerization by its morphological effects.

Methiomeprazine is an active compound.

2-Methoxyidazoxan (RX821002) is a compound that modulates play behavior and can increase play behavior in F344 rats, suggesting that it may modulate play behavior by acting on NEα-2 receptors.