Others

A457 is a prokineticin receptor PKR2 antagonist, with an IC₅₀ of 102 nM. A457 can rescue the cell surface expression and function of P290S PKR2, but not W178S and G234D PKR2.

Valinotricin is a fungal metabolite.

2,3-Dinor-11β-prostaglandin F2α-d₉ is the deuterium labeled 2,3-Dinor-11β-prostaglandin F2α.

Telmapitant is an orally active NK1R antagonist. Telmapitant has antiemetic effect and can be used for the research of delayed onset emesis.

Ethyl-L-NIO hydrochloride is a potent and competitive human dimethylarginine dimethylaminohydrolase 1 (hDDAH-1) inhibitor with an IC₅₀ of 70 μM and a K_i of 32 μM.

HIE-124 is a potent ultra-short acting hypnotic that exhibits a rapid onset of action and a shorter duration of action with no acute tolerance or noticeable side effects. HIE-124 is promising for research of preanesthetic medication and anesthesia inducer.

(S)-3'-Hydroxy blebbistatin is a myosin II inhibitor and is more water-soluble than Blebbistatin.

Vertilmicin combines with FMOC-Cl to form the Vertilmicin-FMOC-Cl adduct, and can be used for the determination of glucosamine sulfate in plasma.

Detoxin D1 is a compound with antihistamine activity and a new type of H1 antagonist. In the suppression of seasonal allergic rhinitis, a daily dose of 10-30 mg has an equivalent and highly effective inhibitory effect compared with placebo and has good safety.

Fibrostatin C (P-23924C) is an orally active prolyl hydroxylase inhibitor that also inhibits collagen biosynthesis. Fibrostatin C also increases the number of cytoplasmic granules immunoreactive with antibodies to collagen I or III. Fibrostatin C inhibits the secretion of type I collagen in Tenon's capsule fibroblasts. Fibrostatin C is promising for research of the wound fibrotic response in the wound of glaucoma filtering surgery.

Alterporriol B is a red pigment, which can be isolated from Alternaria porri. Alternaria porri is the cause of black spot disease in alliums.

SIB-1893 is an active compound.

Trichodecenin II is a fungal metabolite that can be found in conidia of the fungus, Trichoderma viride.

Fluo-3 pentapotassium is a cell-impermeable calcium ion (Ca²⁺) indicator. Fluo-3 pentapotassium itself is not fluorescent, but it becomes fluorescent after binding to calcium ions (Ex/Em = 488/525 nm).

WAY-855 is an active compound.

Pepstanone A is an active compound.

Tetraphyllicine is an alkaloid, which can be isolated from Rauwolfia tetraphylla L. Tetraphyllicine can be used in research about the biosynthetic relationship of indole and indoline alkaloids.

(5R)-Dinoprost is a metabolite produced by cyclooxygenase metabolism of arachidonic acid. (5R)-Dinoprost (Prostaglandin F2β) induces dose-dependent release of hexose containing mucin.

Linadryl is a compound with antihistamine and other effects. It has a variable effect on gastric acid secretion after oral administration, and its effect is about half that of Diphenhydramine (HY-B0303).

Org 27759 is an active compound.