913636-88-1
Chemical Structure
H-0104 dihydrochloride
- CAS No.: 913636-88-1
- Formula:C15H20BrCl2N3O2S
- Molecular Weight:457.21
IUPAC Name: (S)-4-bromo-5-((2-methyl-1,4-diazepan-1-yl)sulfonyl)isoquinoline dihydrochloride
InChIKey: HVNZBMLWOCZURY-IDMXKUIJSA-N
SMILES: C[C@@H]1N(CCCNC1)S(=O)(C2=CC=CC3=C2C(Br)=CN=C3)=O.[H]Cl.[H]Cl
Biological Activity: H-0104 dihydrochloride is a ROCK inhibitor with significant intraocular pressure (IOP)-lowering activity. H-0104 dihydrochloride effectively reduces IOP when administered to monkey eyes. There may not be a direct relationship between the Iop-lowering effect of H-0104 dihydrochloride and ROCK inhibition[1].
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H-0104 dihydrochloride | H-0104 dihydrochloride is a ROCK inhibitor with significant intraocular pressure (IOP)-lowering activity. H-0104 dihydrochloride effectively reduces IOP when administered to monkey eyes. There may not be a direct relationship between the Iop-lowering effect of H-0104 dihydrochloride and ROCK inhibition. | |||||||||||||||||||||
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Keywords