S-Methyl-L-cysteine
Based on 2 publication(s) in Google Scholar
S-Methyl-L-cysteine is a natural product that acts as a substrate in the catalytic antioxidant system mediated by methionine sulfoxide reductase A (MSRA), with antioxidative, neuroprotective, and anti-obesity activities.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 1187-84-4
- Formula: C4H9NO2S
- Molecular Weight:135.18
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Publications Citing Use of MedChemExpress (MCE) S-Methyl-L-cysteine
More
Biological Activity
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Cell Line
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Type | Value | Description | References |
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| HeLa | IC50 |
>50 μM
Compound: 3b
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Cytotoxic activity against HeLa cells
Cytotoxic activity against HeLa cells
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[PMID: 17524640] |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1187-84-4
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Appearance Solid
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Molecular Weight 135.18
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Formula C4H9NO2S
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Color White to off-white
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SMILES
N[C@@H](CSC)C(O)=O
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Synonyms
L-S-Methylcysteine
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year
Publications (2)
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Journal Impact Factor
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Most Recent
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ACS Environ Au
Machine Learning-Assisted Recognition of Environmental Sulfur-Containing Chemicals in Nontargeted Mass Spectrometry Analysis of Inadequate Mass Resolution. [Abstract]2025 Aug 5;5(6):573-582. PMID: 41277996 -
Anal Chem
Exposome-Scale Investigation of Cl-/Br-Containing Chemicals Using High-Resolution Mass Spectrometry, Multistage Machine Learning, and Cloud Computing. [Abstract]2025 Jun 3;97(21):11099-11109. PMID: 40401576
Solvent & Solubility
H2O : 30 mg/mL (221.93 mM; Need ultrasonic and warming)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
For the following dissolution methods, please prepare the working solution directly:
It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: PBS
Solubility: 50 mg/mL (369.88 mM); Clear solution; Need ultrasonic
Purity & Documentation
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Data Sheet (271 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 7.3975 mL | 36.9877 mL | 73.9754 mL | 184.9386 mL |
| 5 mM | 1.4795 mL | 7.3975 mL | 14.7951 mL | 36.9877 mL | |
| 10 mM | 0.7398 mL | 3.6988 mL | 7.3975 mL | 18.4939 mL | |
| 15 mM | 0.4932 mL | 2.4658 mL | 4.9317 mL | 12.3292 mL | |
| 20 mM | 0.3699 mL | 1.8494 mL | 3.6988 mL | 9.2469 mL | |
| 25 mM | 0.2959 mL | 1.4795 mL | 2.9590 mL | 7.3975 mL | |
| 30 mM | 0.2466 mL | 1.2329 mL | 2.4658 mL | 6.1646 mL | |
| 40 mM | 0.1849 mL | 0.9247 mL | 1.8494 mL | 4.6235 mL | |
| 50 mM | 0.1480 mL | 0.7398 mL | 1.4795 mL | 3.6988 mL | |
| 60 mM | 0.1233 mL | 0.6165 mL | 1.2329 mL | 3.0823 mL | |
| 80 mM | 0.0925 mL | 0.4623 mL | 0.9247 mL | 2.3117 mL | |
| 100 mM | 0.0740 mL | 0.3699 mL | 0.7398 mL | 1.8494 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
S-Methyl-L-cysteine Related Classifications
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