2. Signaling Pathways
  3. GPCR/G Protein
    Neuronal Signaling
  4. 5-HT Receptor
  5. 5-HT6 Receptor Isoform
  6. 5-HT6 Receptor Agonist

5-HT6 Receptor Agonist

5-HT6 Receptor Agonists (10):

Cat. No. Product Name Effect Purity
  • HY-100820
    Sarizotan
    		Agonist 98.74%
    Sarizotan (EMD 128130) is an orally active serotonin 5-HT1A receptor and dopamine receptor agonist.
  • HY-14340
    WAY-181187
    		Agonist 98.05%
    WAY-181187 (SAX-187) is a potent and selective full 5-HT6 receptor agonist with a Ki of 2.2 nM and an EC50 of 6.6 nM.
  • HY-13221
    BRL 54443
    		Agonist 99.89%
    BRL 54443 is a potent 5-HT1E/1F receptor agonist (Ki values are 1.1 nM and 0.7 nM respectively); displays > 30-fold selectivity over other 5-HT and dopamine receptors.
  • HY-103110
    ST1936
    		Agonist 99.70%
    ST1936 is a selective, nanomolar affinity 5-HT6 receptor agonist with Ki values of 13 nM, 168 nM and 245 nM for human 5-HT6, 5-HT7 and 5-HT2B receptors, respectively.
  • HY-145862
    5-HT6/5-HT2AR antagonist-1
    		Agonist
    5-HT6/5-HT2AR antagonist-1 is a potent dual 5-HT6/5-HT2AR antagonist with Ki values of 11 nM and 39 nM, respectively.
  • HY-110366
    WAY-181187 oxalate
    		Agonist
    WAY-181187 (SAX-187) oxalate is a potent and selective full 5-HT6 receptor agonist with a Ki of 2.2 nM and an EC50 of 6.6 nM.
  • HY-103130
    EMD386088
    		Agonist
    EMD386088 is a potent serotonin 6 receptor (5-HT6R) agonist.
  • HY-103110A
    ST1936 oxalate
    		Agonist
    ST1936 oxalate is a selective, nanomolar affinity 5-HT6 receptor agonist with Ki values of 13 nM, 168 nM and 245 nM for human 5-HT6, 5-HT7 and 5-HT2B receptors, respectively.
  • HY-103098
    EMDT oxalate
    		Agonist
    EMDT oxalate is a selective 5-HT6 agonist, and has antidepressant effects.
  • HY-118339
    PF-4479745
    		Agonist
    PF-4479745 is a potent and selective 5-HT2C receptor agonist (EC50: 10 nM, ki: 15 nM).