2. Signaling Pathways
  3. GPCR/G Protein
  4. Angiotensin Receptor
  5. AT1 Receptor Isoform
  6. AT1 Receptor Inhibitor

AT1 Receptor Inhibitor

AT1 Receptor Inhibitors (5):

Cat. No. Product Name Effect Purity
  • HY-17005
    Olmesartan medoxomil
    		Inhibitor 99.67%
    Olmesartan medoxomil is a potent and selective angiotensin AT1 receptor inhibitor with IC50 of 66.2 μM.
  • HY-111616
    GSK1820795A
    		Inhibitor 99.76%
    GSK1820795A, as a telmisartan analog, is a selective hGPR132a antagonist. GSK1820795A blocks activation of yeast cells expressing hGPR132a by N-acylamides. GSK1820795A is also a angiotensin II antagonists and partial PPARγ agonists (compound 38).
  • HY-111032
    Allisartan isoproxil
    		Inhibitor
    Allisartan isoproxil (ALS-3) is an orally potent, selective, non-peptide inhibitor of Angiotensin II Type 1. Allisartan isoproxil is also an antihypertensive agent. Allisartan isoproxil may inhibit angiotensin-aldosterone system and oxidative stress. Allisartan isoproxil lowers blood pressure and protects the organs, preventing cerebrovascular damage. Allisartan isoproxil (80-320 mg/kg/d) has shown toxicity in rat models by targeting liver organs.
  • HY-17005R
    Olmesartan medoxomil (Standard)
    		Inhibitor
    Olmesartan medoxomil (Standard) is the analytical standard of Olmesartan medoxomil. This product is intended for research and analytical applications. Olmesartan medoxomil is a potent and selective angiotensin AT1 receptor inhibitor with IC50 of 66.2 μM.
  • HY-17005S
    Olmesartan medoxomil-d6
    		Inhibitor
    Olmesartan medoxomil-d6 (CS 866-d6) is the deuterium labeled Olmesartan medoxomil. Olmesartan medoxomil is a potent and selective angiotensin AT1 receptor inhibitor with IC50 of 66.2 μM[1][2].