28553-12-0
Chemical Structure
Diisononyl phthalate
Synonym(s): DINP
- CAS No.: 28553-12-0
- Formula:C26H42O4
- Molecular Weight:418.61
IUPAC Name: bis(7-methyloctyl) phthalate
InChIKey: HBGGXOJOCNVPFY-UHFFFAOYSA-N
SMILES: O=C(OCCCCCCC(C)C)C1=CC=CC=C1C(OCCCCCCC(C)C)=O
Biological Activity: Diisononyl phthalate (DINP) is an orally active polyvinyl chloride plasticizer and indirect food additive. Diisononyl phthalate activates the ACE/AT1R axis and inhibits the production of NO. Diisononyl phthalate reduces the expression of eNOS. Diisononyl phthalate induces increased blood pressure in mice. Diisononyl phthalate induces monocytic leukemia in rats. Diisononyl phthalate can be used in hypertension-related research[1][2].
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Diisononyl phthalate | 98.0% | Diisononyl phthalate (DINP) is an orally active polyvinyl chloride plasticizer and indirect food additive. Diisononyl phthalate activates the ACE/AT1R axis and inhibits the production of NO. Diisononyl phthalate reduces the expression of eNOS. Diisononyl phthalate induces increased blood pressure in mice. Diisononyl phthalate induces monocytic leukemia in rats. Diisononyl phthalate can be used in hypertension-related research. | ||||||||||||||||||||
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Bis(7-methyl-1-octyl) Phthalate-3,4,5,6-d4 | Bis(7-methyl-1-octyl) Phthalate-3,4,5,6-d4 is the deuterium labeled Bis(7-methyl-1-octyl) Phthalate. | |||||||||||||||||||||
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- [1]. Deng T, et al. Exposure to diisononyl phthalate induced an increase in blood pressure through activation of the ACE/ AT1R axis and inhibition of NO production. Toxicol Lett. 2019;309:42-50. [Content Brief]
- [2]. Lington A W, et al. Chronic toxicity and carcinogenic evaluation of diisononyl phthalate in rats[J]. Fundamental and applied toxicology, 1997, 36(1): 79-89.
