28553-12-0
Chemical Structure
Diisononyl phthalate
Synonym(s): DINP
- CAS No.: 28553-12-0
- Formula:C26H42O4
- Molecular Weight:418.61
IUPAC Name: bis(7-methyloctyl) phthalate
InChIKey: HBGGXOJOCNVPFY-UHFFFAOYSA-N
SMILES: O=C(OCCCCCCC(C)C)C1=CC=CC=C1C(OCCCCCCC(C)C)=O
Biological Activity: Diisononyl phthalate (DINP) is an orally active polyvinyl chloride plasticizer and indirect food additive. Diisononyl phthalate activates the ACE/AT1R axis and inhibits the production of NO. Diisononyl phthalate reduces the expression of eNOS. Diisononyl phthalate induces increased blood pressure in mice. Diisononyl phthalate induces monocytic leukemia in rats. Diisononyl phthalate can be used in hypertension-related research[1][2].
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Diisononyl phthalate | 98.0% | Diisononyl phthalate (DINP) is an orally active polyvinyl chloride plasticizer and indirect food additive. Diisononyl phthalate activates the ACE/AT1R axis and inhibits the production of NO. Diisononyl phthalate reduces the expression of eNOS. Diisononyl phthalate induces increased blood pressure in mice. Diisononyl phthalate induces monocytic leukemia in rats. Diisononyl phthalate can be used in hypertension-related research. | ||||||||||||||||||||
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Bis(7-methyl-1-octyl) Phthalate-3,4,5,6-d4 | Bis(7-methyl-1-octyl) Phthalate-3,4,5,6-d4 is the deuterium labeled Bis(7-methyl-1-octyl) Phthalate. | |||||||||||||||||||||
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Similarity Score 0.84
HY-W011103Diheptyl phthalate -
Similarity Score 0.83
HY-135357Diisohexyl phthalate -
Similarity Score 0.82
HY-W013755Dioctyl phthalate -
Similarity Score 0.80
HY-W011215Dihexyl phthalate -
Similarity Score 0.80
HY-W414916RDiisohexyl phthalate (DIP) (Standard) -
Similarity Score 0.78
HY-W010875Didecyl phthalate -
Similarity Score 0.76
HY-W013816RDipentyl phthalate (Standard) -
Similarity Score 0.74
HY-N17399Bis(2-methylheptyl) phthalate -
Similarity Score 0.72
HY-Y0304RDibutyl phthalate (Standard) -
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References
- [1]. Deng T, et al. Exposure to diisononyl phthalate induced an increase in blood pressure through activation of the ACE/ AT1R axis and inhibition of NO production. Toxicol Lett. 2019;309:42-50. [Content Brief]
- [2]. Lington A W, et al. Chronic toxicity and carcinogenic evaluation of diisononyl phthalate in rats[J]. Fundamental and applied toxicology, 1997, 36(1): 79-89.
