Cannabinoid Receptor
Cannabinoid Receptor
Cannabinoid receptors are currently classified into three groups: central (CB1), peripheral (CB2) and GPR55, all of which are G-protein-coupled. CB1 receptors are primarily located at central and peripheral nerve terminals. CB2 receptors are predominantly expressed in non-neuronal tissues, particularly immune cells, where they modulate cytokine release and cell migration. Recent reports have suggested that CB2 receptors may also be expressed in the CNS. GPR55 receptors are non-CB1/CB2 receptors that exhibit affinity for endogenous, plant and synthetic cannabinoids. Endogenous ligands for cannabinoid receptors have been discovered, including anandamide and 2-arachidonylglycerol.
Cannabinoid Receptor Isoform Specific Products
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Cannabinoid Receptor Inhibitors
(38)
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Cannabinoid Receptor Agonists
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Cannabinoid Receptor Antagonists
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Cannabinoid Receptor Activators
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Cannabinoid Receptor Modulators
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Cannabinoid Receptor Chemical
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Cannabinoid Receptor Inducer
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Cannabinoid Receptor Degrader
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Cannabinoid Receptor Controls
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Cannabinoid Receptor Ligands
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Cannabinoid Receptor Produits associés (450)
Produits associés (450)
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Anticorps (1)
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Cannabinoid Receptor Isoform Comparison
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CH-PIATA
0 ImagesCat. No.: HY-W728163CAS No.: 3085600-43-4CH-PIATA is a synthetic cannabinoid with an acetamide linker. CH-PIATA can be detected as parent substance in blood samples. CH-PIATA has EC50 values of >71 and >176 nM for CB1 and CB2, respectively.
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Δ9-Tetrahydrocannabiorcol
0 ImagesCat. No.: HY-168817CAS No.: 22972-65-2Δ9-Tetrahydrocannabiorcol is structurally similar to known phytocannabinoids.
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Δ9-THCH
0 ImagesCat. No.: HY-168813CAS No.: 36482-24-3Δ9-THCH is structurally similar to known phytocannabinoids.
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AM281 (Standard)
0 ImagesCat. No.: HY-13505RCAS No.: 202463-68-1
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(±)-CBCP
0 ImagesCat. No.: HY-170726CAS No.: 55824-16-3Synonyms: (±)-Cannabichromephorol(±)-CBCP ((±)-Cannabichromephorol) is structurally similar to known phytocannabinoids.
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RTI-371
0 ImagesCat. No.: HY-129215CAS No.: 652978-45-5RTI-371 is a highly selective atypical dopamine transporter (DAT) inhibitor that crosses the blood-brain barrier. RTI-371 exhibits potent inhibitory activity in cell lines transfected with human DAT (IC50 = 8.7 nM) and shows high binding affinity for rat DAT with a Ki value of 7.81 nM. RTI-371 also acts as a positive allosteric modulator of the human cannabinoid 1 receptor (hCB1 receptor), enhancing the activity of cannabinoid receptor agonists in a concentration-dependent manner. RTI-371 can be used for the research of Parkinson's disease.
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Cannabicyclolic acid
0 ImagesCat. No.: HY-W775308CAS No.: 40524-99-0Cannabicyclolic acid is a certified reference material categorized as a photodegradation product of the phytocannabinoid Cannabichromenic acid.
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CHM-FUBIATA
0 ImagesCat. No.: HY-170700CAS No.: 922092-52-2CHM-FUBIATA is structurally similar to known synthetic cannabinoids.
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PB-22 N-Pentanoic acid-3-carboxyindole metabolite
0 ImagesCat. No.: HY-172056CAS No.: 1630022-95-5PB-22 N-Pentanoic acid-3-carboxyindole metabolite is a metabolite of PB-22. PB-22 is a cannabinoid.
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iso-Hexahydrocannabinol
0 ImagesCat. No.: HY-170044CAS No.: 23050-50-2iso-Hexahydrocannabinol is structurally similar to known phytocannabinoids.
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Prostaglandin E2-1-glyceryl ester-d5
0 ImagesCat. No.: HY-114826SSynonyms: PGE2-1-glyceyl ester-d5Prostaglandin E2-1-glyceryl ester-d5 (PGE2-1-glyceyl ester-d5) is deuterium labeled Prostaglandin E2-1-glyceryl ester. Prostaglandin E2-1-glyceryl ester, a Prostaglandin Glycerol Ester, is an endocannabinoid ligand for the CB1 receptor. Prostaglandin E2-1-glyceryl ester induces rapid, transient elevation of intracellular free Ca2+.
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Δ8-iso-THC
0 ImagesCat. No.: HY-168819CAS No.: 23050-47-7Δ8-iso-THC is structurally similar to known phytocannabinoids.
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MJ15 (Standard)
0 ImagesCat. No.: HY-103327RCAS No.: 944154-76-1MJ15 (Standard) is the analytical standard of MJ15 (HY-103327). This product is intended for research and analytical applications. MJ15 is a potent and selective CB1 receptor antagonist with a Ki of 27.2 pM and an IC50 of 118.9 pM for rat CB1 receptors. MJ15 exhibits potency in obesity and hyperlipidemia models. MJ15 inhibits food intake and increases in body weight in diet-induced obese rats and mice.
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(±)-Cannabichromeorcin
0 ImagesCat. No.: HY-129304CAS No.: 55824-09-4(±)-Cannabichromeorcin is a cannabinoid.
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Cannabidihexol
0 ImagesCat. No.: HY-139240CAS No.: 2552798-21-5Synonyms: CBDHCannabidihexol is a phytocannabinoid with analgesic activity in mice.
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3-CAF
0 ImagesCat. No.: HY-172063CAS No.: 2219324-25-93-CAF is a synthetic cannabinoid featuring a 3-carboxylate-indazole structure.
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Cannabigerorcinic acid
0 ImagesCat. No.: HY-116714CAS No.: 69734-83-4Cannabigerorcinic acid is structurally similar to known phytocannabinoids.
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Cannabiorcol
0 ImagesCat. No.: HY-171025CAS No.: 19825-73-1Synonyms: Cannabinol C1; CBN-C1Cannabiorcol (Cannabinol C1) is structurally similar to known phytocannabinoids.
