202463-68-1
202463-68-1
Chemical Structure
AM281
- CAS No.: 202463-68-1
- Formula:C21H19Cl2IN4O2
- Molecular Weight:557.21
IUPAC Name: 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-morpholino-1H-pyrazole-3-carboxamide
InChIKey: AJFFBPZYXRNAIC-UHFFFAOYSA-N
SMILES: O=C(C1=NN(C2=CC=C(Cl)C=C2Cl)C(C3=CC=C(I)C=C3)=C1C)NN4CCOCC4
Biological Activity: AM281 is a selective CB1 receptor antagonist with an IC50 of 9.91 nM. AM281 inhibits CB2 receptor with an IC50 of 13000 nM[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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AM281 | 98.60% | AM281 is a selective CB1 receptor antagonist with an IC50 of 9.91 nM. AM281 inhibits CB2 receptor with an IC50 of 13000 nM. | ||||||||||||||||||||
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AM281 (Standard) | ≥98% | AM281 (Standard) is the analytical standard of AM281. This product is intended for research and analytical applications. AM281 is a selective CB1 receptor antagonist with an IC50 of 9.91 nM. AM281 inhibits CB2 receptor with an IC50 of 13000 nM. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.87
HY-15443RAM251 (Standard) -
Similarity Score 0.80
HY-14136RRimonabant (Standard) -
Similarity Score 0.80
HY-14137RRimonabant Hydrochloride (Standard) -
Similarity Score 0.78
HY-103326NIDA-41020 -
Similarity Score 0.71
HY-110206AM6545 -
Similarity Score 0.71
HY-120423AM-6538 -
Similarity Score 0.71
HY-107019Surinabant -
Similarity Score 0.71
HY-105238JHU-75528 -
Similarity Score 0.69
HY-116649CB1 antagonist 2 -
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