Fungal
An antifungal agent is a drug that selectively eliminates fungal pathogens from a host with minimal toxicity to the host.
Classes: 1. Polyene Antifungal Drugs: Amphotericin, nystatin, and pimaricin interact with sterols in the cell membrane (ergosterol in fungi, cholesterol in humans) to form channels through which small molecules leak from the inside of the fungal cell to the outside. 2. Azole Antifungal Drugs: Fluconazole, itraconazole, and ketoconazole inhibit cytochrome P450-dependent enzymes (particularly C14-demethylase) involved in the biosynthesis of ergosterol, which is required for fungal cell membrane structure and function. 3. Allylamine and Morpholine Antifungal Drugs: lylamines (naftifine, terbinafine) inhibit ergosterol biosynthesis at the level of squalene epoxidase. The morpholine drug, amorolfine, inhibits the same pathway at a later step. 4. Antimetabolite Antifungal Drugs: 5-Fluorocytosine acts as an inhibitor of both DNA and RNA synthesis via the intracytoplasmic conversion of 5-fluorocytosine to 5-fluorouracil.
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Fungal Related Products (2737)
Related Products (2737)
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Antibodies (1)
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Related Compound Screening Libraries (1)
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Copper naphthenate
0 ImagesCat. No.: HY-W072994CAS No.: 1338-02-9Copper naphthenate is an organocopper compound with the properties of a fungicide, preservative, oil-borne protectant, and toxicant. Copper naphthenate increases serum and urine copper levels in exposed populations, causes skin irritation, and induces intraperitoneal toxicity in rats. Copper naphthenate inhibits the growth of decay fungi and molds on moso bamboo, kills the free-living stages of Ichthyophthirius multifiliis, and controls wood-boring insects and termites.
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2,5-Furandimethanol (Standard)
0 Images2,5-Furandimethanol (Standard) is the analytical standard of 2,5-Furandimethanol (HY-W017782). This product is intended for research and analytical applications. 2,5-Furandimethanol (2,5-Bis(hydroxymethyl)furan) is a building block for the enzymatic synthesis of bio-based polyesters. 2,5-Furandimethanol is also a metabolite of Phellinus linteus. 2,5-Furandimethanol affects leukemia. 2,5-Furandimethanol can be used in fungal infection research.
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Concanamycin G
0 ImagesCat. No.: HY-N14427CAS No.: 144730-82-5Concanamycin G has antifungal, antiviral, immunosuppressive, cytotoxic and other activities, and is a specific inhibitor of V-type ATPase (Ki=0.02 nM), which is an important tool for biochemical research.
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Fluindapyr (Standard)
0 ImagesCat. No.: HY-W753375RCAS No.: 1383809-87-7Clenbuterol (hydrochloride) (Standard) is the analytical standard of Clenbuterol (hydrochloride). This product is intended for research and analytical applications. Clenbuterol (NAB-365) hydrochloride, a selective β2-adrenergic agonist, enhances skeletal muscle strength and hypertrophy. Clenbuterol hydrochloride induces growth factor mRNA, activates astrocytes, and protects rat brain tissue against ischemic damage.
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Neocopiamycin A
0 ImagesCat. No.: HY-N14489CAS No.: 89989-28-6Neocopiamycin A is broad-spectrum resistant to Gram-positive bacteria, yeast and filamentous fungi.
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Azaconazole
0 ImagesCat. No.: HY-119830CAS No.: 60207-31-0Azaconazole is an agriculture fungicide, and can be used for controlling powdery mildew on crops and bean rust.
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Bupirimate
0 ImagesBupirimate is a systemic fungicide that inhibits adenosine deaminase (ADA). Bupirimate is widely used in the cultivation of fruit trees, vegetables, flowers, and other crops to control powdery mildew.
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Antifungal agent 119
0 ImagesCat. No.: HY-169203Antifungal agent 119 (compund T23) is an antifungal agent that targets type I reduced NADH oxidoreductase. Antifungal agent 119 carries an azide group and can be used for click chemistry reactions..
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Dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride (42% w/w in methanol)
![Dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride (42% w/w in methanol)](https://file.medchemexpress.com/product_pic/hy-w010790.gif "Click to View Dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride (42% w/w in methanol) Product Detail")
0 ImagesCat. No.: HY-W010790CAS No.: 27668-52-6Dimethyloctadecyl[3-(trimethoxysilyl) propyl]ammonium chloride is a quaternary ammonium silane monomer-based disinfectant/antimicrobial agent. Dimethyloctadecylammonium chloride exhibits bactericidal activity against Gram-positive and Gram-negative bacteria, as well as fungicidal activity against Candida albicans in solution; it can form a hydrophobic glass coating that displays bactericidal activity against Gram-positive and Gram-negative bacteria but has limited fungicidal activity against Candida albicans.
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WML-01
0 ImagesCat. No.: HY-178717CAS No.: 3057478-36-8WML-01 is a fungicide with EC50s of 0.079, 0.72 and 2.02 μg/mL against F. graminearum, F. fujikuroi and S. sclerotiorum. WML-01 disrupts the cell membrane of F. graminearum and induces deposition of lipid droplets. WML-01 inhibits Deoxynivalenol (DON) (HY-N6684) biosynthesis with no cross-resistance and strongly suppresses ribosomal subunit assembly, impairing protein synthesis. WML-01 effectively controls the fusarium head blight (FHB) epidemic.
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Bupirimate (Standard)
0 ImagesCat. No.: HY-133216RCAS No.: 41483-43-6Bupirimate (Standard) is the analytical standard of Bupirimate (HY-133216). This product is intended for research and analytical applications. Bupirimate is a systemic fungicide that inhibits adenosine deaminase (ADA). Bupirimate is widely used in the cultivation of fruit trees, vegetables, flowers, and other crops to control powdery mildew.
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CDA-IN-4
0 ImagesCat. No.: HY-173448CAS No.: 466656-34-8CDA-IN-4 (compound VS-24) is a chitin deacetylase (CDA) inhibitor. CDA-IN-4 shows a 61.2% protective effect against rice blast at a concentration of 100 μg/mL.
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Glomosporin
0 ImagesCat. No.: HY-N14582CAS No.: 288631-37-8Glomosporin is a cyclic ester peptide antifungal antibiotic, and it has moderate anti-Aspergillus flavus (including Aspergillus Niger and Aspergillus Niger), yeast activity (MIC is 16 μg/mL).
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Pradimicin B
0 ImagesCat. No.: HY-N14434CAS No.: 117704-66-2Pradimicin B is an antibiotic. Pradimicin B has strong antifungal and yeast activity.
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Aminothiazole (Standard)
0 ImagesAminothiazole (Standard) is the analytical standard of Aminothiazole. This product is intended for research and analytical applications. Aminothiazole (2-Aminothiazole), a typical heterocyclic amine, is a precursor for the synthesis of biologically active molecules including sulfur agents, biocides, fungicides, antibiotics, dyes and chemical reaction accelerators.
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Acrylamidine
0 ImagesCat. No.: HY-N14991CAS No.: 19408-49-2Acrylamidine has weak anti-mold and yeast activity.
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Antifungal agent 135
0 ImagesCat. No.: HY-178051Antifungal agent 135 (Compound C2), an antifungal agent, is a Succinate dehydrogenase (SDH) inhibitor with an IC50 of 1.99 μM. Antifungal agent 135 has potent antifungal activities against Valsa mali, Sclerotinia sclerotiorum and Phytophthora capsici with EC50 s of 0.280, 1.11 and 0.130 mg/L, respectively. Antifungal agent 135 shows protective and curative activities against Phytophthora capsici and Valsa mali by effectively disrupting hyphal structural integrity and inhibiting mycelial growth.
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SDH-IN-33
0 ImagesCat. No.: HY-178346SDH-IN-33 (Compound I-9) is a succinate dehydrogenase inhibitor. SDH-IN-33 exhibits excellent fungicidal activity with an EC50 of 0.07 μg/mL. SDH-IN-33 inhibits R. solani succinate dehydrogenase (RsSDH) with an IC50 0.35 μg/mL. SDH-IN-33 can be used for the study of fungal infection.
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Antifungal agent 171
0 ImagesCat. No.: HY-184730Antifungal agent 171 is a mitochondrial complex III inhibitor with a Botrytis cinerea IC50 of 6.48 mg/L. Antifungal agent 171 interferes with respiratory metabolism by binding to mitochondrial complex III and exhibits broad-spectrum inhibitory activity against Valsa mali, Botrytis cinerea, and Physalospora piricola. Antifungal agent 171 can be used for the research of valsa mali infection, botrytis cinerea infection, physalospora piricola infection.
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Methoxyanigorufone
0 ImagesCat. No.: HY-N8921CAS No.: 56252-05-2Synonyms: 2-O-MethylanigorufoneMethoxyanigorufone (compound 4) is a compound that can be isloated from Musa acuminata var. "Yangambi km 5".
