Parasite
Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.
Parasite Isoform Specific Products
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Parasite Related Products (2477)
Related Products (2477)
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Related Compound Screening Libraries (1)
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Parasite Isoform Comparison
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Hydroxychloroquine-d5
0 ImagesCat. No.: HY-W031727S1Hydroxychloroquine-d5 is the deuterium labeled Hydroxychloroquine. Hydroxychloroquine is a synthetic antimalarial agent which can also inhibit Toll-like receptor 7/9 (TLR7/9) signaling. Hydroxychloroquine is efficiently inhibits SARS-CoV-2 infection in vitro.
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Homidium chloride
0 ImagesHomidium chloride is a potent antiparasitic agent exhibiting activity against Trypanosoma rhodesiense and Trypanosoma congolense. Homidium chloride can reduce parasitaemia in murine models of infection. Homidium chloride can be used for trypanosomiasis research.
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Antitrypanosomal agent 33
0 ImagesCat. No.: HY-184202Antitrypanosomal agent 33 is a potent antitrypanosomal agent with activity against Trypanosoma cruzi intracellular amastigotes, Trypanosoma brucei brucei, and Trypanosoma brucei rhodesiense. Antitrypanosomal agent 33 can be used for the research of trypanosomiasis, chagas disease.
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Cymbopogon citratus extract
0 ImagesCat. No.: HY-N20595Synonyms: Cymbopogon titrtus extract; Lemongrass extract; Cymbopogon extractCymbopogon citratus extract (Cymbopogon titrtus extract) is a lemongrass (Cymbopogon Citratus DC (Stapf.)) extract with antibacterial, antiprotozoal, antirheumatic, antitumor, cardioprotective, anti-inflammatory and gastric protective properties.
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Pulixin
0 ImagesCat. No.: HY-N10197CAS No.: 2826264-81-5Pulixin prevents FREP1 from binding to P. falciparum-infected cell lysate. Pulixin blocks the transmission of the parasite to mosquitoes with an EC50 of 11 µM. Pulixin also inhibits the proliferation of asexual-stage P. falciparum with an EC50 of 47 nM.
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Proguanil-d4
0 ImagesCat. No.: HY-B0806S1CAS No.: 1189805-15-9Proguanil-d4 is the deuterium labeled Proguanil. Proguanil, an antimalarial proagent, is metabolized to the active metabolite Cycloguanil (HY-12784). Proguanil is a dihydrofolate reductase (DHFR) inhibitor.
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3′,4′,5′,5,6,7-Hexamethoxyflavone
0 Images3′,4′,5′,5,6,7-Hexamethoxyflavone is a flavonoid with antiprotozoal activity. 3′,4′,5′,5,6,7-Hexamethoxyflavone inhibits trypanosoma bruceirhodesiense with IC50 of 21.3 μM (8.58 g/mL).
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Fenbutatin oxide
0 ImagesCat. No.: HY-133004CAS No.: 13356-08-6Fenbutatin oxide is an organotin acaricide.
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5-Methoxycanthin-6-one
0 ImagesCat. No.: HY-N9194CAS No.: 15071-56-45-Methoxycanthin-6-one is an orally active inhibitor of Leishmania strains. 5-Methoxycanthin-6-one shows cytotoxicity with an IC50 of 5.44 μg/mL against Ailanthus altissima cells.
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Longestin
0 ImagesCat. No.: HY-126812CAS No.: 131774-53-3Synonyms: KS-505aLongestin (KS-505a) is a specific inhibitor of phosphodiesterase with antitrypanosomal activity, which is derived from Streptomyces argenteolus. Longestin is promising for research of anti-amnesia agent.
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Antimalarial agent 42
0 ImagesCat. No.: HY-163997Antimalarial agent 42 (Compound 2) is an antimalarial agent, that inhibits Plasmodium falciparum in the phase of asexual blood stages (IC50 <0.5μM) and gametocytes (IC50 is 0.14 μM).
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Tigolaner-d4
0 ImagesCat. No.: HY-109077STigolaner-d4 is deuterium labeled Tigolaner. Tigolaner (BAY-1272858) acts on γ-aminobutyric acid (GABA) and glutamate-gated chloride channels. Tigolaner has antiparasitic activity.
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Triclabendazole sulfoxide-13C,d3
0 ImagesCat. No.: HY-136450S1Synonyms: TCBZ-SO-13C,d3Triclabendazole sulfoxide-13C,d3 is the 13C- and deuterium labeled Triclabendazole sulfoxide. Triclabendazole sulfoxide (TCBZ-SO) is an orally active ABCG2 inhibitor with antiparasitic activity. Triclabendazole sulfoxide inhibits ABCG2-mediated active efflux and ATPase activity. Triclabendazole sulfoxide increases the intracellular accumulation of Mitoxantrone (HY-13502). Triclabendazole sulfoxide reduces the apical-directed transepithelial transport of Nitrofurantoin and Danofloxacin, while increasing their basolateral-directed transepithelial transport. Triclabendazole sulfoxide elevates the plasma levels of sulfasalazine in wild-type mice. Triclabendazole sulfoxide decreases ABCG2-mediated secretion of Nitrofurantoin into milk in wild-type lactating mice. Triclabendazole sulfoxide can be used in the research of insecticidal agents and cancers such as breast cancer.
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Pyridaben-d13
0 ImagesCat. No.: HY-B0817SCAS No.: 2468638-05-1Pyridaben-d13 is the deuterium labeled Pyridaben. Pyridaben is a mitochondrial electron transport inhibitor (METI) acaricide that promotes the formation of damaging oxygen and nitrogen radicals. Pyridaben selectively inhibits complex I (NADH dehydrogenase) with an IC50 value of 2.4 nM (assay sites: rat liver and bovine heart mitochondria). Pyridaben also significantly inhibits rat mitochondrial mtNOS function.
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Crotamiton-d5
0 ImagesCat. No.: HY-W743562
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Lactucin (Standard)
0 ImagesLactucin (Standard) is the analytical standard of Lactucin. This product is intended for research and analytical applications. Lactucin is an anti-inflammatory agent. Lactucin induces cancer cell apoptosis. Lactucin also shows analgesic, anticancer and antimalarial activities[4].
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(S)-GSK1379725A
0 ImagesCat. No.: HY-145431CAS No.: 2359618-49-6(S)-GSK1379725A (compound AU1) is a selective bromodomain and PHD finger containing transcription factor (BPTF) bromodomain inhibitor with a Kd of 2.8 μM. (S)-GSK1379725A shows to be selective for BPTF over BRD4 bromodomain. (S)-GSK1379725A shows antimalarial activity.
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Succinate dehydrogenase-IN-2
0 ImagesCat. No.: HY-163890CAS No.: 3023681-83-3Succinate dehydrogenase-IN-2 (Compound 12x) is an inhibitor for succinate dehydrogenase (SDH) with an IC50 of 1.22 mg/L. Succinate dehydrogenase-IN-2 exhibits antifungal activity, that inhibits S. sclerotiorum, V. mali, G. graminis, R. solani and B. cinerea with EC50 of 0.52-3.42 mg/L.
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25-Hydroperoxycycloart-23-en-3β-ol
0 ImagesCat. No.: HY-N17550CAS No.: 173740-54-025-Hydroperoxycycloart-23-en-3β-ol is an anticancer, antibacterial, and antimalarial agent. 25-Hydroperoxycycloart-23-en-3β-ol can be isolated from Blepharodon nitidum. 25-Hydroperoxycycloart-23-en-3β-ol exhibits anti-Mycobacterium tuberculosis and antileishmanial activities. 25-Hydroperoxycycloart-23-en-3β-ol shows significant cytotoxic activity against a panel of tumor cell lines (large cell lung cancer, melanoma, colon adenocarcinoma, chronic myelogenous leukemia).
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Imidocarb (Standard)
0 ImagesPargyline (hydrochloride) (Standard) is the analytical standard of Pargyline (hydrochloride). This product is intended for research and analytical applications. Pargyline hydrochloride is an irreversible monoamine oxidase (MAO) inhibitor with Kis of 13 μM and 0.5 μM for MAO-A and MAO-B, respectively. Pargyline hydrochloride has antihypertensive and anticancer activities. Pargyline (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
