602-52-8
602-52-8
Chemical Structure
Homidium chloride
- CAS No.: 602-52-8
- Formula:C21H20ClN3
- Molecular Weight:349.86
IUPAC Name: 3,8-diamino-5-ethyl-6-phenylphenanthridin-5-ium chloride
InChIKey: BITVSRNAFFZUFW-UHFFFAOYSA-N
SMILES: NC1=CC2=C(C3=C([N+](CC)=C2C4=CC=CC=C4)C=C(N)C=C3)C=C1.[Cl-]
Biological Activity: Homidium chloride is a potent antiparasitic agent exhibiting activity against Trypanosoma rhodesiense and Trypanosoma congolense. Homidium chloride can reduce parasitaemia in murine models of infection. Homidium chloride can be used for trypanosomiasis research[1][2].
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Homidium chloride | Homidium chloride is a potent antiparasitic agent exhibiting activity against Trypanosoma rhodesiense and Trypanosoma congolense. Homidium chloride can reduce parasitaemia in murine models of infection. Homidium chloride can be used for trypanosomiasis research. | |||||||||||||||||||||
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References
- [1]. Hill J. Studies on isometamidium: the effect of isometamidium, homidium and pyrithidium on the infectivity of trypanosomes for mice. Br J Pharmacol Chemother. 1965 Dec;25(3):658-63. [Content Brief]
- [2]. Codjia V, et al. Epidemiology of bovine trypanosomiasis in the Ghibe valley, southwest Ethiopia. 3. Occurrence of populations of Trypanosoma congolense resistant to diminazene, isometamidium and homidium. Acta Trop. 1993 Apr;53(2):151-63. [Content Brief]
Keywords
