Pulixin
Pulixin prevents FREP1 from binding to P. falciparum-infected cell lysate. Pulixin blocks the transmission of the parasite to mosquitoes with an EC50 of 11 µM. Pulixin also inhibits the proliferation of asexual-stage P. falciparum with an EC50 of 47 nM.
For research use only. We do not sell to patients.
- CAS No.: 2826264-81-5
- Formula: C14H11NO4
- Molecular Weight:257.24
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Plasmodium |
Microbial Metabolite |
Pulixin, a fungal metabolite, inhibits Plasmodium falciparum transmission and infection. It does not show cytotoxic effects at a concentration of 116 µM or lower[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2826264-81-5
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Molecular Weight 257.24
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Formula C14H11NO4
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SMILES
O=C1C2=C(O)C=C(O)C=C2C3=C(O1)C=C(N)C=C3C
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Structure Classification
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Initial Source
Purpureocillium lilacinum
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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