Pulixin
Pulixin prevents FREP1 from binding to P. falciparum-infected cell lysate. Pulixin blocks the transmission of the parasite to mosquitoes with an EC50 of 11 µM. Pulixin also inhibits the proliferation of asexual-stage P. falciparum with an EC50 of 47 nM.
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- CAS No.: 2826264-81-5
- Formule: C14H11NO4
- Masse moléculaire:257.24
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
Description
IC50 & Target
[1]|
Plasmodium |
Microbial Metabolite |
In Vitro
Pulixin, a fungal metabolite, inhibits Plasmodium falciparum transmission and infection. It does not show cytotoxic effects at a concentration of 116 µM or lower[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2826264-81-5
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Masse moléculaire 257.24
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Formule C14H11NO4
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SMILES
O=C1C2=C(O)C=C(O)C=C2C3=C(O1)C=C(N)C=C3C
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Structure Classification
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Initial Source
Purpureocillium lilacinum
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)