1891-29-8
1891-29-8
Chemical Structure
Lactucin
- CAS No.: 1891-29-8
- Formula:C15H16O5
- Molecular Weight:276.28
IUPAC Name: (3aR,4S,9aS,9bR)-4-hydroxy-9-(hydroxymethyl)-6-methyl-3-methylene-3,3a,4,5,9a,9b-hexahydroazuleno[4,5-b]furan-2,7-dione
InChIKey: VJQAFLAZRVKAKM-VZLIPTOUSA-N
SMILES: OCC([C@]1([H])[C@]2([H])[C@]([C@H](CC(C)=C13)O)([H])C(C(O2)=O)=C)=CC3=O
Biological Activity: Lactucin is an anti-inflammatory agent. Lactucin induces cancer cell apoptosis. Lactucin also shows analgesic, anticancer and antimalarial activities[1][2][3][4].
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Lactucin | 99.72% | Lactucin is an anti-inflammatory agent. Lactucin induces cancer cell apoptosis. Lactucin also shows analgesic, anticancer and antimalarial activities. | ||||||||||||||||||||
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Lactucin (Standard) | ≥98% | Lactucin (Standard) is the analytical standard of Lactucin. This product is intended for research and analytical applications. Lactucin is an anti-inflammatory agent. Lactucin induces cancer cell apoptosis. Lactucin also shows analgesic, anticancer and antimalarial activities. | ||||||||||||||||||||
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References
- [1]. Dang T, et al. Sesquiterpenoids with diverse carbon skeletons from the roots of Cichorium glandulosum and their anti-inflammatory activities. Fitoterapia. 2019 Jul;136:104170. [Content Brief]
- [2]. Gromek D, et al. Biologically active preparations from Lactuca virosa L. Phytotherapy Research, 1992, 6(5): 285-287.
- [3]. Zhang F H, et al. Lactucin induces potent anti-cancer effects in HL-60 human leukemia cancer cells by inducing apoptosis and sub-G1 cell cycle arrest. Bangladesh Journal of Pharmacology, 2016, 11(2): 478-484.
- [4]. Bischoff TA, et al. Antimalarial activity of lactucin and lactucopicrin: sesquiterpene lactones isolated from Cichorium intybus L. J Ethnopharmacol. 2004 Dec;95(2-3):455-7. [Content Brief]
