Parasite
Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.
Alle Parasite Isoform-spezifische Produkte anzeigen
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Parasite Verwandte Produkte (2477)
Verwandte Produkte (2477)
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Related Compound Screening Libraries (1)
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Parasite Isoform Comparison
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Mirincamycin hydrochloride
0 ImagesMirincamycin (hydrochloride) (U-24729 A), a compound used to inhibit malaria, has a protective effect against the early liver stages of Plasmodium but fails to kill dormant liver stages of Plasmodium in a rhesus monkey model.
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Sulfaquinoxaline-d4
0 ImagesArt. -Nr.: HY-B1282SCAS. Nr.: 1329652-02-9Sulfaquinoxaline-d4 is the deuterium labeled Sulfaquinoxaline. Sulfaquinoxaline is an antimicrobial for veterinary use, with activity against a broad spectrum of Gram-negative and Gram-positive bacteria. Sulfaquinoxaline is used to prevent coccidiosis and bacterial infections.
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Benzoximate
0 ImagesArt. -Nr.: HY-116511CAS. Nr.: 29104-30-1Benzoximate is an acaricide that inhibits fruit tree red spider mite Panonychys ulmi (Koch).
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SJ000025081
0 ImagesArt. -Nr.: HY-136448CAS. Nr.: 421571-66-6SJ000025081 is a dihydropyridine and acts as a potent antimalarial agent. SJ000025081 results in an obvious suppression of the parasitemia in a murine malaria model infected with P. yoelii.
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Antimalarial agent 19
0 ImagesArt. -Nr.: HY-152614CAS. Nr.: 2897630-89-4Antimalarial agent 19 (compound 6e) is an antimalarial active agent. Antimalarial agent 19 has antimalarial activity for the blood stage of P. falciparum K1 and P. berghei with EC50 values of 0.3 µM, 15.3 µM, respectively. Antimalarial agent 19 has good aqueous solubility, intestinal permeability and microsomal stability compared to gamhepathiopine.
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GSK575594A
0 ImagesArt. -Nr.: HY-111161CAS. Nr.: 909418-68-4GSK575594A is a modulator of the nicotinic acetylcholine receptor (nAChR) in Ascaris suum. GSK575594A enhances muscle contractions induced by acetylcholine (ACh) by binding to the allosteric binding site between subunits within the transmembrane domain of nAChR. At a concentration of 3 μM, GSK575594A significantly increased the contraction induced by ACh in Ascaris suum (Emax increased from 1.19 g to 1.51 g). GSK575594A may be used in research within the field of antiparasitic studies.
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Cycloguanil-d6 (hydrochloride)
0 ImagesArt. -Nr.: HY-12784AS1CAS. Nr.: 2712364-69-5Synonyms: Chlorguanide triazine-d6 hydrochlorideCycloguanil-d6 (Chlorguanide triazine-d6) hydrochloride is the deuterium labeled Cycloguanil hydrochloride (HY-12784A). Cycloguanil hydrochloride is a dihydrofolate reductase (DHFR) inhibitor with an IC50 of 10.8 μM against human DHFR. Cycloguanil hydrochloride blocks the folate metabolic pathway, thereby affecting nucleotide synthesis and interfering with DNA replication. Cycloguanil hydrochloride inhibits DHFR in Plasmodium and is thus used in malaria research. Cycloguanil hydrochloride also potently inhibits DHFR in human cancer cells and blocks the transcriptional activity of STAT3, thereby exhibiting anticancer activity.
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Antimalarial agent 11
0 ImagesArt. -Nr.: HY-146769CAS. Nr.: 1214454-56-4Antimalarial agent 11 (compound 1), a spirocyclic chromane, is a potent antimalarial agent. Antimalarial agent 11 exhibits excellent potency with an EC50 of 350 nM against the Chloroquine-resistant Dd2 strain. Antimalarial agent 11 has EC50s of 1.48 µM and 1.81 µM against D6 and ARC08-022 strains, respectively.
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Diarctigenin
0 ImagesArt. -Nr.: HY-162155Diarctigenin is a selective Leishmania major dihydrofolate reductase-thymidylate synthase (LmDHFR-TS) inhibitor. Diarctigenin can be used for the research of tropical disease.
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2,4-Diacetylphloroglucinol (Standard)
0 ImagesArt. -Nr.: HY-118448RCAS. Nr.: 2161-86-62,4-Diacetylphloroglucinol (Standard) is the analytical standard of 2,4-Diacetylphloroglucinol (HY-118448). This product is intended for research and analytical applications. 2,4-Diacetylphloroglucinol is a polyketide antibiotic produced by Pseudomonas fluorescens. 2,4-Diacetylphloroglucinol exhibits broad-spectrum toxicity against various organisms such as bacteria, fungi, oomycetes, and nematodes. 2,4-Diacetylphloroglucinol can also inhibit plant pathogens and affect the root development of tomato seedlings.
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1,2,3,4-Tetrahydronorharman-1-one
0 ImagesArt. -Nr.: HY-W268334CAS. Nr.: 17952-82-81,2,3,4-Tetrahydronorharman-1-one is a manzamine alkaloid with activity against infectious and tropical parasitic diseases from an Indonesian sponge.
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Neoprocurcumenol
0 ImagesArt. -Nr.: HY-N8585CAS. Nr.: 102130-91-6Neoprocurcumenol is a larvicidal compound that exerts significant toxicity on mosquito larvae with LC50 and LC 90 values of 13.69 and 23.92 ppm, respectively.
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Ornidazole-d5
0 ImagesArt. -Nr.: HY-B0508SCAS. Nr.: 2747915-64-4Synonyms: Ro 7-0207-d5Ornidazole-d5 is deuterium labeled Ornidazole. Ornidazole (Ro 7-0207) is a nitroimidazole derivative with anti-trichomonad activity and in vitro activity against a variety of anaerobic bacteria. Ornidazole inhibits Sonic hedgehog (Shh) signaling pathway, exhibits antitumor activity. Ornidazole can be used in research of Crohn’s disease.
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Aklavin
0 ImagesArt. -Nr.: HY-121473CAS. Nr.: 60504-57-6Aklavin is a structural analog of Aclacinomycin A (HY-N2306) produced by Streptomyces strain A 1165. Aklavin possesses Z-DNA-inducing and stabilizing activities, along with antibiotic, anti-phage and broad-spectrum antimicrobial activities. Aklavin inhibits the proliferation of various viruses (such as influenza virus and poliovirus) and interferes with their nucleoprotein synthesis, while also exhibiting inhibitory effects on staphylococci, mycobacteria and specific fungi. Aklavin blocks phage-induced bacterial lysis by regulating host-parasite interactions. Aklavin shows specific toxicity to fertilized eggs and mice, and does not alter the splicing of the SMN2 gene.
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Chlorphenoxamine hydrochloride
0 ImagesChlorphenoxamine hydrochloride, an antihistamine and anticholinergic agent is a GPCR antagonist. Chlorphenoxamine hydrochloride inhibits multiple lethal viral diseases, such as SARS-CoV, MERS-CoV, EBOV and malaria. Chlorphenoxamine hydrochloride shows anti-filovirus activity against both EBOV and Marburg virus (MARV) with IC50s of 1.1 μM and 6.2 μM, respectively. Chlorphenoxamine hydrochloride is used for allergic conditions, urticaria, viral diseases and Parkinson’s disease.
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CpCDPK1/TgCDPK1-IN-2
0 ImagesArt. -Nr.: HY-128398CAS. Nr.: 1236038-23-5CpCDPK1/TgCDPK1-IN-2 (Compound 7r) is a CpCDPK1 and TgCDPK1 inhibitor with IC50 values of 12 and 5 nM, respectively. CpCDPK1/TgCDPK1-IN-2 can be used in the research of apicomplexan protozoa-related diseases, such as the research of T. gondii, C. parvum and C. hominus infection.
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(+)-Secolongifolene-diol
0 ImagesArt. -Nr.: HY-137034CAS. Nr.: 53587-37-4(+)-Secolongifolene-diol is a sesquiterpene, that can be isolated from the marine fungal Drechslera sp. (+)-Secolongifolene-diol exhibits slightly weak effectiveness in antioxidation, antimicrobial and antifouling aspects.
