SIRT1 Activator

SIRT1 Activators (20):

Cat. No.	Product Name	Effect	Purity

HY-123033A

Nicotinamide riboside chloride	Activator	99.59%
Nicotinamide riboside Chloride, an orally active NAD⁺ precursor, increases NAD⁺ levels and activates SIRT1 and SIRT3.

HY-15145

SRT 1720 Hydrochloride	Activator	99.92%
SRT 1720 Hydrochloride is a selective and orally active activator of SIRT1 with an EC₅₀ of 0.10 μM, and shows less potent activities on SIRT2 and SIRT3.

HY-15145A

SRT 1720 dihydrochloride	Activator	98.51%
SRT 1720 dihydrochloride is a selective and orally active activator of SIRT1 with an EC₅₀ of 0.10 μM, and shows less potent activities on SIRT2 and SIRT3.

HY-122936

Tanshindiol C

Activator

98.47%

Tanshindiol C is a S-adenosylmethionine-competitive EZH2 (HY-10532

SRT 1720

Activator 99.82%

SRT 1720 is a selective activator of human SIRT1 with an EC_1.5 of 0.16 μM, and shows less potent activities for SIRT2 and SIRT3 with EC_1.5s of 37 μM and > 300 μM, respectively.

HY-15262

SRT 2104

Activator 99.76%

SRT 2104 is a first-in-class, highly selective and brain-permeable activator of the NAD⁺ dependent deacetylase Sirt1, increases Sirt1 protein, but shows no effect on Sirt1 mRNA.

HY-19759

SRT 2183

Activator 98.17%

SRT 2183 is a selective Sirtuin-1 (SIRT1) activator with an EC_1.5 value of 0.36 μM.

HY-104073

CAY10602

Activator 98.65%

CAY10602 is a SIRT1 activator.

HY-124037

SRT 1460

Activator 98.92%

SRT 1460, a potent Sirtuin-1 (SIRT1) activator with an EC_1.5 value of 2.9 μM, shows good selectivity for activation of SIRT1 versus SIRT2 and SIRT3 (EC1.5>300 μM), and is more potent than Resveratrol and the closest sirtuin homologues.

HY-N0704

Agrimol B

Activator 99.75%

Agrimol B, a polyphenol, is an orally active and potent SIRT1 activator.

HY-N0341

Scopolin

Activator 99.46%

Scopolin is a coumarin isolated from Arabidopsis thaliana (Arabidopsis) roots.

HY-19634

YK-3-237

Activator 99.59%

YK-3-237, a SIRT1 activator, targets mutant p53.

HY-123033

Nicotinamide riboside

Activator

Nicotinamide riboside, an orally active NAD⁺ precursor, increases NAD⁺ levels and activates SIRT1 and SIRT3.

HY-N3504

Ophiopogonin D'

Activator 99.85%

Ophiopogonin D', isolated from the tubers of Ophiopogon japonicus, is a rare naturally occurring C₂₉ steroidal glycoside.

HY-N9398

3β,6α,12β-Dammar-E-20(22)-ene-3,6,12,25-tetraol

Activator

3β,6α,12β-Dammar-E-20(22)-ene-3,6,12,25-tetraol, a SIRT1 activator, exhibits significant stimulation of SIRT1 activity.

HY-N10125

Ainsliadimer C

Activator

Ainsliadimer C, a potential activator of SIRT1, ameliorates inflammatory responses in adipose tissue.

HY-123033B

Nicotinamide riboside tartrate

Activator

Nicotinamide riboside tartrate, an orally active NAD⁺ precursor, increases NAD⁺ levels and activates SIRT1 and SIRT3.

HY-123033C

Nicotinamide riboside malate

Activator

Nicotinamide riboside malate, an orally active NAD⁺ precursor, increases NAD⁺ levels and activates SIRT1 and SIRT3.

HY-E70008

Lumbokinase capsules

Activator

Lumbokinase capsules attenuates myocardial ischemia-reperfusion (I-R) injury through the activation of Sirt1 signaling, and thus enhances autophagic flux and reduces I-R-induced oxidative damage, inflammation and apoptosis.

HY-148712

SIRT6 activator 12q

Activator 98.01%

SIRT6 activator 12q is potent, selective and orally active SIRT6 activator with IC₅₀ values of 171.20, >200, >200, >200, 0.58 µM for SIRT1, SIRT2, SIRT3, SIRT5, SIRT6, respectively.

[email protected]

609-228-6898

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