925432-73-1
925432-73-1
Chemical Structure
SRT 1460
- CAS No.: 925432-73-1
- Formula:C26H29N5O4S
- Molecular Weight:507.60
IUPAC Name: 3,4,5-trimethoxy-N-(2-(3-(piperazin-1-ylmethyl)imidazo[2,1-b]thiazol-6-yl)phenyl)benzamide
InChIKey: SBEWVVLMFLTQFE-UHFFFAOYSA-N
SMILES: O=C(NC1=CC=CC=C1C2=CN3C(SC=C3CN4CCNCC4)=N2)C5=CC(OC)=C(OC)C(OC)=C5
Biological Activity: SRT 1460, a potent Sirtuin-1 (SIRT1) activator with an EC1.5 value of 2.9 μM, shows good selectivity for activation of SIRT1 versus SIRT2 and SIRT3 (EC1.5>300 μM), and is more potent than Resveratrol and the closest sirtuin homologues[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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SRT 1460 | 98.16% | SRT 1460, a potent Sirtuin-1 (SIRT1) activator with an EC1.5 value of 2.9 μM, shows good selectivity for activation of SIRT1 versus SIRT2 and SIRT3 (EC1.5>300 μM), and is more potent than Resveratrol and the closest sirtuin homologues. | ||||||||||||||||||||
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References
Keywords
