Drug Derivative
Drug derivative
Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.
References:
- [1]. Vardanyan RS, et al. Fentanyl-related compounds and derivatives: current status and future prospects for pharmaceutical applications. Future Med Chem. 2014 Mar;6(4):385-412.x
- [2]. Ghosh AK, et al. Urea Derivatives in Modern Drug Discovery and Medicinal Chemistry. J Med Chem. 2020 Mar 26;63(6):2751-2788.x
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Drug Derivative Related Products (4010)
Related Products (4010)
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5,7-Dimethoxy-4'-hydroxyflavan
0 ImagesCat. No.: HY-N16807CAS No.: 103963-45-75,7-Dimethoxy-4'-hydroxyflavan is a natural flavonoid.
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(5Z,13E)-6,9Alpha-epoxy-11alpha-hydroxy-15-oxoprosta-5,13-dienoate
0 ImagesCat. No.: HY-180615CAS No.: 100311-07-7Synonyms: 15-Dehydro-prostaglandin I2(5Z,13E)-6,9Alpha-epoxy-11alpha-hydroxy-15-oxoprosta-5,13-dienoate (15-Dehydro-prostaglandin I2) is an analogue of prostaglandin I2.
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LY 154045
0 ImagesCat. No.: HY-111133CAS No.: 91706-86-4LY 154045 is an active compound.
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Nordefrin
0 ImagesCat. No.: HY-B1708CAS No.: 74812-63-8Synonyms: (±)-CobefriNordefrin ((±)-Cobefri), a Norepinephrine (HY-13715) derivative, is a vasoconstrictor agent.
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Garcimultiflorone J
0 ImagesCat. No.: HY-N9883CAS No.: 2010216-41-6Garcimultiflorone J is a natural phenolic compound.
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Celangulin III
0 ImagesCat. No.: HY-N7873CAS No.: 144379-42-0Celangulin III is a natural product that can be found in Tripterygium wilfordii Hook. f., Begonia spp..
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Denticulatain E
0 ImagesCat. No.: HY-N17025CAS No.: 1919050-76-2Denticulatain E is a natural flavonoid.
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Budesonide 21-palmitate
0 ImagesCat. No.: HY-185063CAS No.: 102638-08-4Budesonide 21-palmitate is a lipophilic ester prodrug of Budesonide (HY-13580), can be formulated into liposomal formulations. Budesonide 21-palmitate exhibts anti-inflammatory and anti-allergic activities. Budesonide 21-palmitate can achieve selective passive targeted delivery of drugs to tumor tissues (such as lung tumors). Budesonide 21-palmitate can be used for drug delivery in inflammatory and allergic research.
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Daturataturin A aglycone
0 ImagesCat. No.: HY-N3691CAS No.: 904665-71-0Daturataturin A aglycone is a natural steroid.
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Decanoyl-L-carnitine chloride
0 ImagesCat. No.: HY-145503CAS No.: 369651-88-7Decanoyl-L-carnitine chloride is an ester derivative of L-carnitine, which is an important cofactor of fatty acid metabolism.
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Durianol A
0 ImagesCat. No.: HY-N17112CAS No.: 1941203-91-3Durianol A is a natural coumarin.
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Poncimarin
0 ImagesCat. No.: HY-N11413CAS No.: 55916-48-8Poncimarin is a coumarin compound extracted from Poncirus trifoliata. Poncimarin can be used for research on inflammatory conditions.
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Macrophylloside B
0 ImagesCat. No.: HY-N17036CAS No.: 179457-67-1Macrophylloside B is a natural iridoid.
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Wikstroelide E
0 ImagesCat. No.: HY-N16802CAS No.: 66107-38-8Wikstroelide E is a natural diterpene.
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AD11
0 ImagesCat. No.: HY-121155CAS No.: 74670-75-0AD11, a sulfonamide derivative, exhibits anticonvulsant potency in the rat.
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Anticancer agent 240
0 ImagesCat. No.: HY-161845CAS No.: 3039831-27-8Anticancer agent 240 (compound 9b) is an 8-quinolinesulfonamide derivative with a cytotoxicity activity. Anticancer agent 240 shows inhibitory activity in Caco-2, SNB-19, A-549, and SKOV-3 cell line IC50 values of 0.26, 0.38, 0.40 and 4.16 μM.
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Oxyphyllone D
0 ImagesCat. No.: HY-N17148CAS No.: 1190094-25-7Oxyphyllone D is a natural sesquiterpene.
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Adenostemmoic acid B
0 ImagesCat. No.: HY-N17003CAS No.: 130217-16-2Adenostemmoic acid B is a natural diterpene.
