Drug Derivative
Drug derivative
Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.
References:
- [1]. Vardanyan RS, et al. Fentanyl-related compounds and derivatives: current status and future prospects for pharmaceutical applications. Future Med Chem. 2014 Mar;6(4):385-412.x
- [2]. Ghosh AK, et al. Urea Derivatives in Modern Drug Discovery and Medicinal Chemistry. J Med Chem. 2020 Mar 26;63(6):2751-2788.x
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Drug Derivative Related Products (3996)
Related Products (3996)
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Spongipregnoloside B
0 ImagesCat. No.: HY-N19223CAS No.: 552297-98-0Spongipregnoloside B is a pregnane diglycoside found in the rhizomes of Dioscorea spongiosa. Spongipregnoloside B can be used in osteoporosis research.
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S-27609
0 ImagesCat. No.: HY-W852084CAS No.: 151751-58-5S-27609 is an imidazoquinoline with antiviral and antitumour properties. S-27609 can induce peripheral blood mononuclear cells to produce various cytokines such as interferon-α (IFN-α), tumor necrosis factor-α (TNF-α), and interleukin-1β (IL-1β). S-27609 is promising for research of viral infections (e.g., herpes virus) and tumors.
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3-Methyl-2-(3-methylbut-3-enoyl)-furan
0 ImagesCat. No.: HY-N16750CAS No.: 78173-38-33-Methyl-2-(3-methylbut-3-enoyl)-furan is a Furan derivative. 3-Methyl-2-(3-methylbut-3-enoyl)furan is a characteristic component of essential oils from the genus Elsholtzia.
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Hydrocortisone-21-lysinate
0 ImagesCat. No.: HY-137211CAS No.: 95924-98-4Hydrocortisone-21-lysinate is an active compound.
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Lancifodilactone I
0 ImagesCat. No.: HY-N7998CAS No.: 883153-31-9Lancifodilactone I is a natural product that can be found in Schisandra chinensis?(Turcz.) Baill..
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DRF-4015
0 ImagesCat. No.: HY-149547CAS No.: 905838-14-4DRF-4015 (Compound 22) is a betulinic acid derivative with antitumor activity.
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Trifunctional sphingosine
0 ImagesCat. No.: HY-N15947CAS No.: 2089062-80-4Trifunctional sphingosine is a clickable sphingoid base derivative. Trifunctional sphingosine can be used to study the biological function of sphingoid bases. Trifunctional lipids may overcome several challenges in interrogating lipid biology: their fast metabolism, their weak and transient (but functionally important) interactions with proteins, and the difficulty in tagging them without disturbing the cellular location.
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Salcolin B
0 ImagesCat. No.: HY-N16766CAS No.: 369390-52-3Synonyms: Tricin 4'-O-(erythro-β-guaiacylglyceryl) etherSalcolin B is a natural flavonoid.
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4-Fluoro phenibut hydrochloride
0 ImagesCat. No.: HY-118583ACAS No.: 1858241-03-8Synonyms: β-(4-Fluorophenyl)-GABA hydrochloride; F-Phenibut hydrochloride4-Fluoro phenibut (β-(4-Fluorophenyl)-GABA) hydrochloride is a Gabapentinoid and is structurally similar to known nootropics.
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9''-O-Acetylsalcolin A
0 ImagesCat. No.: HY-N17172CAS No.: 910864-92-59''-O-Acetylsalcolin A is a natural flavonoid.
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5,7-Dimethoxy-4'-hydroxyflavan
0 ImagesCat. No.: HY-N16807CAS No.: 103963-45-75,7-Dimethoxy-4'-hydroxyflavan is a natural flavonoid.
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(5Z,13E)-6,9Alpha-epoxy-11alpha-hydroxy-15-oxoprosta-5,13-dienoate
0 ImagesCat. No.: HY-180615CAS No.: 100311-07-7Synonyms: 15-Dehydro-prostaglandin I2(5Z,13E)-6,9Alpha-epoxy-11alpha-hydroxy-15-oxoprosta-5,13-dienoate (15-Dehydro-prostaglandin I2) is an analogue of prostaglandin I2.
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LY 154045
0 ImagesCat. No.: HY-111133CAS No.: 91706-86-4LY 154045 is an active compound.
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Nordefrin
0 ImagesCat. No.: HY-B1708CAS No.: 74812-63-8Synonyms: (±)-CobefriNordefrin ((±)-Cobefri), a Norepinephrine (HY-13715) derivative, is a vasoconstrictor agent.
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Garcimultiflorone J
0 ImagesCat. No.: HY-N9883CAS No.: 2010216-41-6Garcimultiflorone J is a natural phenolic compound.
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Celangulin III
0 ImagesCat. No.: HY-N7873CAS No.: 144379-42-0Celangulin III is a natural product that can be found in Tripterygium wilfordii Hook. f., Begonia spp..
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Denticulatain E
0 ImagesCat. No.: HY-N17025CAS No.: 1919050-76-2Denticulatain E is a natural flavonoid.
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Budesonide 21-palmitate
0 ImagesCat. No.: HY-185063CAS No.: 102638-08-4Budesonide 21-palmitate is a lipophilic ester prodrug of Budesonide (HY-13580), can be formulated into liposomal formulations. Budesonide 21-palmitate exhibts anti-inflammatory and anti-allergic activities. Budesonide 21-palmitate can achieve selective passive targeted delivery of drugs to tumor tissues (such as lung tumors). Budesonide 21-palmitate can be used for drug delivery in inflammatory and allergic research.
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Daturataturin A aglycone
0 ImagesCat. No.: HY-N3691CAS No.: 904665-71-0Daturataturin A aglycone is a natural steroid.
