Drug Intermediate
Drug Iintermediate
Drug intermediates are used as raw materials for the production of bulk drugs, or they can refer to a material produced during synthesis of an API that must undergo further molecular change or processing before it becomes an API. Drug intermediates are hygienically formulated using high grade raw materials and they are used in the pharmaceutical and cosmetic industry[1][2].
References:
- [1]. Ma HC, et al. Homochiral Covalent Organic Framework for Catalytic Asymmetric Synthesis of a Drug Intermediate. J Am Chem Soc. 2020 Jul 22;142(29):12574-12578. [Content Brief]
- [2]. Ramachary D B, et al. Development of pharmaceutical drugs, drug intermediates and ingredients by using direct organo‐click reactions[J]. 2008.
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Drug Intermediate Related Products (4714)
Related Products (4714)
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(1R,2S)-1-tert-Butoxycarbonylamino-2-vinylcyclopropanecarboxylic acid
0 Images(1R,2S)-1-tert-Butoxycarbonylamino-2-vinylcyclopropanecarboxylic acid is a drug intermediate for synthesis of various active compounds.
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Methyl 3-((tert-butoxycarbonyl)amino)-5-iodothiophene-2-carboxylate
0 ImagesMethyl 3-((tert-butoxycarbonyl)amino)-5-iodothiophene-2-carboxylate is a drug intermediate for synthesis of various active compounds.
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4-Hydroxy-N,N,2-trimethyl-1H-benzimidazole-6-carboxamide
0 Images4-Hydroxy-N,N,2-trimethyl-1H-benzimidazole-6-carboxamide is a drug intermediate for synthesis of various active compounds.
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Methyl 2-bromo-4-fluorobenzo[d]thiazole-6-carboxylate
![Methyl 2-bromo-4-fluorobenzo[d]thiazole-6-carboxylate](https://file.medchemexpress.com/product_pic/hy-w021608.gif "Click to View Methyl 2-bromo-4-fluorobenzo[d]thiazole-6-carboxylate Product Detail")
0 ImagesMethyl 2-bromo-4-fluorobenzo[d]thiazole-6-carboxylate is a drug intermediate for synthesis of various active compounds.
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4-Hydroxy-3-methoxy-5-nitrobenzoic acid
0 ImagesSynonyms: 3-Nitro-4-hydroxy-5-methoxybenzoic acid; 5-Nitrovanillic acid; 3-Methoxy-4-hydroxy-5-nitrobenzoic acid4-Hydroxy-3-methoxy-5-nitrobenzoic acid (3-Nitro-4-hydroxy-5-methoxybenzoic acid) is a drug intermediate for synthesis of various active compounds.
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((3aR,4R,6R,6aR)-6-((E)-4-(Hydroxyimino)-2-oxo-3,4-dihydropyrimidin-1(2H)-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methyl isobutyrate
![((3aR,4R,6R,6aR)-6-((E)-4-(Hydroxyimino)-2-oxo-3,4-dihydropyrimidin-1(2H)-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methyl isobutyrate](https://file.medchemexpress.com/product_pic/hy-45219.gif "Click to View ((3aR,4R,6R,6aR)-6-((E)-4-(Hydroxyimino)-2-oxo-3,4-dihydropyrimidin-1(2H)-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methyl isobutyrate Product Detail")
0 ImagesSynonyms: Uridine,2',3'-o-(1-methylethylidene)-,4-oxidechemicalbook,5'-(2-methylpropanoate)((3aR,4R,6R,6aR)-6-((E)-4-(Hydroxyimino)-2-oxo-3,4-dihydropyrimidin-1(2H)-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methyl isobutyrate (Uridine,2',3'-o-(1-methylethylidene)-,4-oxidechemicalbook,5'-(2-methylpropanoate)) is a drug intermediate for synthesis of various active compounds.
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5-Methyl-2-(pyrimidin-2-yl)benzoicacid
0 Images5-Methyl-2-(pyrimidin-2-yl)benzoicacid is a drug intermediate for synthesis of various active compounds.
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1-(4-Chloro-2-hydroxyphenyl)ethan-1-one
0 Images1-(4-Chloro-2-hydroxyphenyl)ethan-1-one is a drug intermediate for synthesis of various active compounds.
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2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxaldehyde
![2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxaldehyde](https://file.medchemexpress.com/product_pic/hy-42451.gif "Click to View 2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxaldehyde Product Detail")
0 ImagesCat. No.: HY-42451CAS No.: 1211443-55-82-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxaldehyde is a drug intermediate for synthesis of various active compounds.
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1,4-Cyclohexanedione
0 Images1,4-Cyclohexanedione is a drug intermediate. 1,4-Cyclohexanedione is an accepted substrate of EryKR1 domain which takes on a certain biocatalyst activity and stereospecificity.
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5-(Piperazin-1-yl)isoquinoline hydrochloride
0 Images5-(Piperazin-1-yl)isoquinoline hydrochloride is a drug intermediate for synthesis of various active compounds.
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Thiosalicylic acid
0 ImagesThiosalicylic acid (2-Mercaptobenzoic acid) is an organosulfur compound bearing both sulfhydryl and carboxyl functional groups. Thiosalicylic acid acts as a desulfurizing agent. Thiosalicylic acid also serves as a ligand to synthesize azosulfonamide derivatives with antibacterial and antifungal activities, as well as their Fe3+, Cu2+ and Hg2+ chelates.
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6,7-Dimethoxy-2-tetralone
0 Images6,7-Dimethoxy-2-tetralone is a drug intermediate for synthesis of various active compounds.
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Elsulfavirine
0 ImagesSynonyms: R-1206Elsulfavirine (R-1206) is an orally active human carbonic anhydrase (carbonic anhydrase, CA) inhibitor and an allosteric inhibitor of HIV-1 non-nucleoside reverse transcriptase (NNRT). Elsulfavirine also targets and blocks the interaction between adenylosuccinate lyase (ADSL) and insulin-induced gene proteins INSIG1/2, blocks SREBP-1-mediated de novo lipid synthesis, and inhibits the proliferation of liver cancer cells. The combination of Elsulfavirine and Lenvatinib (HY-10981) produces a synergistic anti-tumor effect. Elsulfavirine is converted into the active metabolite VM1500A in vivo, blocks the DNA polymerase activity of reverse transcriptase, and inhibits HIV-1 replication. Elsulfavirine exhibits a Ki of 1960 nM-52400 nM against human carbonic anhydrase isoforms including I, VII, VI, VA, VB, IX, XIII, XIV. Elsulfavirine is used in studies related to HIV-1 infection and liver cancer.
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5’-O-(4,4’-Dimethoxytrityl)-2’-O-methyluridine
0 ImagesCat. No.: HY-W025438CAS No.: 103285-22-95’-O-(4,4’-Dimethoxytrityl)-2’-O-methyluridine is a 2'-O-methyluridine derivative bearing a 5'-O-(4,4'-dimethoxytrityl) protecting group.5’-O-(4,4’-Dimethoxytrityl)-2’-O-methyluridine serves as a starting material for synthesis of a conformationally rigid cyclic uridylic acid derivative.
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N-Methoxy-N-methylacetamide
0 ImagesN-Methoxy-N-methylacetamide can efficiently acetylate polycarbonyl compounds. As an important intermediate, N-Methoxy-N-methylacetamide can be used for the synthesis of other active compounds.
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7-Bromoisoquinoline
0 Images7-Bromoisoquinoline is a brominated isoquinoline and synthetic precursor that constructs the isoquinoline functional group at the C17 position of target molecules. 7-Bromoisoquinoline serves as a key synthetic intermediate for the synthesis of cortistatin A-derived anti-angiogenic steroidal analogs (e.g., 7-tributylstannyl isoquinoline). 7-Bromoisoquinoline.
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Olivetolic acid
0 ImagesOlivetolic acid is a biosynthetic precursor of cannabinol acid (CBGA). Olivetolic acid exhibits a modest anticonvulsant effect in a mouse model of Dravet syndrome. Olivetolic acid can be used for the study of convulsion.
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(R)-Tetrahydropapaverine hydrochloride
0 Images(R)-Tetrahydropapaverine hydrochloride is the isomer of Tetrahydropapaverine hydrochloride (HY-N0137), and can be used as an experimental control. Tetrahydropapaverine hydrochloride is one of the Tetrahydroisoquinolines. Tetrahydropapaverine hydrochloride has neurotoxic effects on dopamine neurons.
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Cyclohexanecarboxylic acid
0 ImagesCyclohexanecarboxylic acid is a Valproate structural analogue. Cyclohexanecarboxylic acid is an essential intermediate for the aromatization of Shikimic acid (HY-N0130) by mammals. Cyclohexanecarboxylic acid has anticonvulsant action.
