Olivetolic acid
Based on 1 Customer Validation
Olivetolic acid is a biosynthetic precursor of cannabinol acid (CBGA). Olivetolic acid exhibits a modest anticonvulsant effect in a mouse model of Dravet syndrome. Olivetolic acid can be used for the study of convulsion.
For research use only. We do not sell to patients.
- Purity: 99.90%
- CAS No.: 491-72-5
- Formula: C12H16O4
- Molecular Weight:224.25
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Scn1a+/- mice (P14-16, male and female) generated by breeding 129.Scn1a+/- mice with C57BL/6J mice were used as the model of Dravet syndrome[1]
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Dosage:10, 30, 100 mg/kg
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Administration:i.p. for a single dose
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Result:Achieved a modest increase in the hyperthermia-induced generalized tonic-clonic seizure (GTCS) temperature threshold by approximately 0.4°C at a dose of 100 mg/kg.
Showed no significant anticonvulsant effects at doses of 10 mg/kg and 30 mg/kg in the same mouse model.
Chemical Information
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CAS No. 491-72-5
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Appearance Solid
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Molecular Weight 224.25
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Formula C12H16O4
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Color White to off-white
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SMILES
O=C(O)C1=C(CCCCC)C=C(O)C=C1O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 250 mg/mL (1114.83 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.4593 mL | 22.2965 mL | 44.5931 mL | 111.4827 mL |
| 5 mM | 0.8919 mL | 4.4593 mL | 8.9186 mL | 22.2965 mL | |
| 10 mM | 0.4459 mL | 2.2297 mL | 4.4593 mL | 11.1483 mL | |
| 15 mM | 0.2973 mL | 1.4864 mL | 2.9729 mL | 7.4322 mL | |
| 20 mM | 0.2230 mL | 1.1148 mL | 2.2297 mL | 5.5741 mL | |
| 25 mM | 0.1784 mL | 0.8919 mL | 1.7837 mL | 4.4593 mL | |
| 30 mM | 0.1486 mL | 0.7432 mL | 1.4864 mL | 3.7161 mL | |
| 40 mM | 0.1115 mL | 0.5574 mL | 1.1148 mL | 2.7871 mL | |
| 50 mM | 0.0892 mL | 0.4459 mL | 0.8919 mL | 2.2297 mL | |
| 60 mM | 0.0743 mL | 0.3716 mL | 0.7432 mL | 1.8580 mL | |
| 80 mM | 0.0557 mL | 0.2787 mL | 0.5574 mL | 1.3935 mL | |
| 100 mM | 0.0446 mL | 0.2230 mL | 0.4459 mL | 1.1148 mL |
Olivetolic acid Related Classifications
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