2. Signaling Pathways
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  4. Drug Intermediate

Drug Intermediate

Drug Iintermediate

Drug intermediates are used as raw materials for the production of bulk drugs, or they can refer to a material produced during synthesis of an API that must undergo further molecular change or processing before it becomes an API. Drug intermediates are hygienically formulated using high grade raw materials and they are used in the pharmaceutical and cosmetic industry[1][2].

Drug Intermediate Related Products (4352):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-130705
    Previtamin D3
    		98.68%
    Previtamin D3 is an orally active, thermolabile steroidal compound that generates vitamin D3, as well as biologically inactive lumisterol and tachysterol. Previtamin D3 is synthesized in the skin of humans and rats via the UV-B-mediated photoconversion of 7-dehydrocholesterol. Previtamin D3 lacks direct anti-rachitic activity, and its in vivo activity relies on the vitamin D3 it produces. Previtamin D3 can be used in studies related to rickets and vitamin D metabolism.
    Previtamin D3
  • HY-135638
    Imatinib Acid
    		Control 99.73%
    Imatinib Acid is an analogue of Imatinib (HY-15463).
    Imatinib Acid
  • HY-P3519A
    ACV Tripeptide TFA
    ACV Tripeptide TFA, a tripeptide, is the first dedicated intermediate in the biosynthetic pathway leading to the penicillin and cephalosporin classes of β-lactam natural products in bacteria and fungi. ACV Tripeptide TFA is is synthesized nonribosomally by the ACV synthetase (ACVS) enzyme, which is encoded by the 11 kb The pchAB gene encodes this enzyme. ACV Tripeptide TFA can be used for the biosynthesis of β-lactam antibiotics.
    ACV Tripeptide TFA
  • HY-41631
    Boc-Pyr-Oet
    		98.0%
    Boc-Pyr-Oet ((S)-Ethyl-N-Boc-pyroglutamate) is a derivative of L-Pyroglutamic acid (HY-76082). Boc-Pyr-Oet can be used for the synthesis of agents or other compounds.
    Boc-Pyr-Oet
  • HY-N16102
    13:0 Lyso PE
    		99%
    13:0 Lyso PE is an intermediate. 13:0 Lyso PE can be used to synthesize tumor-triggered, targeted ammonium bicarbonate liposomes.
    13:0 Lyso PE
  • HY-W017289S
    4,4′-Dipyridyl-d8
    4,4′-Dipyridyl-d8 is the deuterium labeled 4,4'-Dipyridyl (HY-017289). 4,4′-Dipyridyl is a heterocyclic compound. 4,4′-Dipyridyl is utilized as an electronic and photosensitive building block and bidentate ligand in supramolecular chemistry. 4,4′-Dipyridyl can also be used as a drug intermediate in the synthesis of paraquat, a widely used herbicide.
    4,4′-Dipyridyl-d<sub>8</sub>
  • HY-W011934
    1,3-Dibromo-5-methylbenzene
    		99.99%
    1,3-Dibromo-5-methylbenzene is an aromatic halide that can be used for the synthesis of other active compounds.
    1,3-Dibromo-5-methylbenzene
  • HY-66004
    4-Acetamidophenyl acetate
    4-Acetamidophenyl acetate is an impurity of Acetaminophen (HY-66005). 4-Acetamidophenyl acetate acts as an intermediate in the synthesis of Acetaminophen. Acetaminophen is a selective COX-2 inhibitor (IC50=25.8 μM), and is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor.
    4-Acetamidophenyl acetate
  • HY-W010533
    (E)-2-Methyl-2-pentenoic acid
    		99.82%
    (E)-2-Methyl-2-pentenoic acid is the component can be used to synthesize the cytotoxic natural product Lactimidomycin.
    (E)-2-Methyl-2-pentenoic acid
  • HY-W010594
    Tetrahydrothiophen-3-one
    		99.72%
    Tetrahydrothiophen-3-one is an endogenous metabolite. Tetrahydrothiophen-3-one is a pharmaceutical intermediate that can be used to synthesize thiazole compounds. Tetrahydrothiophen-3-one exists in natural food and has good safety.
    Tetrahydrothiophen-3-one
  • HY-16031B
    AFP464 dihydrochloride
    		99.67%
    AFP464 (NSC710464) dihydrochloride is a prodrug of Aminoflavone (HY-132974) and an agonist of the aryl hydrocarbon receptor (AhR). AFP464 dihydrochloride downregulates the expression of α6-integrin (α6-integrin), inhibits breast tumor growth, reduces the population of tumor-initiating cells, disrupts mammosphere structure, induces the formation of mucin lake clusters, triggers DNA damage, and exerts antiproliferative activity. AFP464 dihydrochloride is rapidly converted to Aminoflavone by nonspecific esterases in plasma and cell culture media. AFP464 dihydrochloride is applicable to research related to breast cancer.
    AFP464 dihydrochloride
  • HY-119326
    N-Formylmethamphetamine
    N-Formylmethamphetamine is an impurity in the synthesis of methamphetamine. N-Formylmethamphetamine is also a by-product of the Nagai reaction.
    N-Formylmethamphetamine
  • HY-107832
    Ketoisophorone
    		99.90%
    Ketoisophorone (4-Oxoisophorone) is the active small molecule that can be used as building block.
    Ketoisophorone
  • HY-W012846A
    L-Threitol
    		98.0%
    L-Threitol (L-1,2,3,4-Butanetetrol) is a four-carbon sugar alcohol. L-Threitol serves as an important pharmaceutical intermediate and can be used in the synthesis of other active compounds, such as anticancer agents and chiral compounds.
    L-Threitol
  • HY-121305B
    L-Ribulose (solution)
    		99.85%
    L-Ribulose solution is a 1 M solution of L-Ribulose in water. L-Ribulose is an L-form pentulose. L-Ribulose serves as a key precursor for the synthesis of L-ribose and L-nucleoside analogs.
    L-Ribulose (solution)
  • HY-W001251
    3,5-Dimethoxybenzoic acid
    		99.66%
    3,5-Dimethoxybenzoic acid is an aromatic organic acid and antifungal agent. 3,5-Dimethoxybenzoic acid can also be used as an intermediate for anticancer agents. 3,5-Dimethoxybenzoic acid can be isolated from the leaves of Melia azedarach. 3,5-Dimethoxybenzoic acid exhibits antifungal activity against A. rabiei with an MIC of 0.125 mg/mL. 3,5-Dimethoxybenzoic acid has anti-wrinkle, anti-inflammatory, antioxidant, and skin regeneration effects.
    3,5-Dimethoxybenzoic acid
  • HY-176844
    eIF4A-IN-1 intermediate
    eIF4A-IN-1 intermediate (Compound 71E) is an intermediate of Eukaryotic translation initiation factor 4A (eIF4A) inhibitor. eIF4A-IN-1 intermediate can be used as a cytotoxic payload for synthesis of antibody-drug conjugates (ADCs).
    eIF4A-IN-1 intermediate
  • HY-W001996R
    6-Hydroxynicotinic acid (Standard)
    6-Hydroxynicotinic acid (Standard) is the analytical standard of 6-Hydroxynicotinic acid (HY-W001996). This product is intended for research and analytical applications. 6-Hydroxynicotinic acid is an intermediate in the oxidation of Nicotinic acid (HY-B0143) by Pseudomonas fluorescens and metabolite. 6-Hydroxynicotinic acid can be isolated from root exudates of Cucumis melo. 6-Hydroxynicotinic acid disrupts the Auxin signaling pathway. 6-Hydroxynicotinic acid inhibits haustoria precursor formation in Phlipanche aegyptiaca.
    6-Hydroxynicotinic acid (Standard)
  • HY-W016323
    2-Benzylaniline
    2-Benzylaniline is an intermediate. 2-Benzylaniline can be used to synthesize Compound 15. Compound 15 shows an affinity for the D3 receptor with a Ki of 4654 nM. 2-Benzylaniline can be used in research on mental illnesses.
    2-Benzylaniline
  • HY-I0736S
    Isonicotinic acid-d4
    		98.12%
    Isonicotinic acid-d4 is the deuterium labeled Isonicotinic acid (HY-I0736). Isonicotinic acid is an Isoniazid (HY-B0329) metabolite. The Isonicotinic acid derivative Enisamium inhibits the replication of multiple subtypes of influenza A virus.
    Isonicotinic acid-d<sub>4</sub>