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  4. Fluorescent Dye

Fluorescent Dye

Fluorescence is a phenomenon of photoluminescence in luminescence. When an atom is irradiated by light, some electrons around the nucleus jump from their original orbitals to higher energy orbitals under the influence of light energy, i.e., from the ground state to the first or second excited single-line state, etc. Due to the instability of the first or second excited singlet state, the electron returns from the excited singlet state to the ground state accompanied by released energy, resulting in fluorescence.

Fluorescent dyes can be covalently bound or physically adsorbed in the structure of the substance. The fluorescence properties allow for the characterization, localization and quantitative analysis of the labeled object. Fluorescent dyes have shown great potential for the detection of proteins, nucleic acids, cells, and immunoassays, attributed to the advantages in non-radioactive contamination, simple experimental operation and easy observation.

Fluorescent dyes have penetrated many fields such as pharmacology, physiology, environmental science, and information science, as well as functional studies of proteins and drug screening.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-177656D
    Cy3 labled Pivicasiran sodium
    Cy3 labled Pivicasiran sodium is a Cy3 labled Pivicasiran sodium.
    Cy3 labled Pivicasiran sodium
  • HY-W247614
    D 131
    D 131 is an orange organic indoline dye. The absorption maxima of D131 in solution is λ=425 nm.
    D 131
  • HY-D2342
    SARS-CoV-2 3CLpro probe-1
    SARS-CoV-2 3CLpro probe-1 (Compound probe 3) is a selective and activity-based probe for the SARS-CoV-2 3CL protease. SARS-CoV-2 3CLpro probe-1 can detect endogenously expressed 3CLpro in SARS-CoV-2-infected cells.
    SARS-CoV-2 3CLpro probe-1
  • HY-D2537
    Cy3-PEG2000-N3
    Cy3-PEG2000-N3 is a Cy3 (HY-D0822)-azide fluorescent dye used to label for protein and nucleic acid. Cy3-PEG2000-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    Cy3-PEG2000-N3
  • HY-127008
    N-Butylfluorescein
    N-Butylfluorescein is an alkyl-substituted fluorescein, can be used for synthesis of fluorogenic substrates for assaying phosphatidylinositol-specific phospholipase C.
    N-Butylfluorescein
  • HY-132595E
    Cy3 labled Teprasiran sodium
    Cy3 labled Teprasiran sodium is a Cy3 labled Teprasiran sodium.
    Cy3 labled Teprasiran sodium
  • HY-177650D
    Cy3 labled Nucresiran sodium
    Cy3 labled Nucresiran sodium is a Cy3 labled Nucresiran sodium.
    Cy3 labled Nucresiran sodium
  • HY-D2758
    TAMRA DBCO, 5-isomer
    TAMRA DBCO, 5-isomer is a derivative of TAMRA fluorescent isomer with a DBCO functional group. TAMRA DBCO, 5-isomer undergoes strain-promoted azide-alkyne cycloaddition (SPAAC) under copper-free catalytic conditions. TAMRA DBCO, 5-isomer serves as a FRET acceptor for FAM fluorophores. TAMRA DBCO, 5-isomer can label proteins, peptides, nucleic acids and all azide-modified biomolecules, and is suitable for fluorescence imaging and flow cytometry to quantify intracellular SPAAC reactions.
    TAMRA DBCO, 5-isomer
  • HY-P4334
    Bz-RGFFL-4MβNA
    Bz-RGFFL-4MβNA (Bz-Arg-Gly-Phe-Phe-Leu-4MβNA) is a peptide and can be used fluorogenic substrate.
    Bz-RGFFL-4MβNA
  • HY-D3392
    Thalidomide-cyanine 5
    Thalidomide-cyanine 5 is a fluorescent probe prepared by conjugating the CRBN binder Thalidomide (HY-14658) with the near-infrared fluorescent dye Cy5. Thalidomide-cyanine 5 binds to DDB1-CRBN protein complex with a Kd of 121.6 nM. Thalidomide-cyanine 5 binds to CRBN to form a binary complex, and is mainly used for the visual tracking research of degradants such as PROTAC (Ex/Em = 650/665 nm).
    Thalidomide-cyanine 5
  • HY-P11265
    YQGN-7
    YQGN-7 is a targeted fluorescent probe for the gonadotropin-releasing hormone receptor (RnRHR). YQGN-7 exhibits high selectivity and affinity for breast cancer cells (KD = 217.8 nM). YQGN-7 achieves precise visualization of the primary and metastatic lesions of breast cancer by targeting the highly expressed GnRHR in tumor cells. YQGN-7 can be used in the research of breast cancer breast-conserving surgery (BCS).
    YQGN-7
  • HY-159692E
    Cy3 labled AZD8701 sodium
    Cy3 labled AZD8701 sodium is a Cy3 labled AZD8701 sodium.
    Cy3 labled AZD8701 sodium
  • HY-W127780
    Rhodamine 6G perchlorate
    Rhodamine dyes are membrane-permeable cationic fluorescent probes that specifically recognize mitochondrial membrane potentials, thereby attaching to mitochondria and producing bright fluorescence, and at certain concentrations, rhodamine dyes have low toxicity to cells, so they are commonly used to detect mitochondria in animal cells, plant cells, and microorganisms.
    Rhodamine 6G perchlorate
  • HY-158541
    A4 glycan, 2-AB labelled
    A4 glycan, 2-AB labelled (A4 N-linked oligosaccharide, 2-AB labelled) is a N-polysaccharide protein and a multifunctional fluorescent linker. The resulting conjugates exhibit high sensitivity and specificity by mimicking the antennal elements of N-glycans.
    A4 glycan, 2-AB labelled
  • HY-D1582
    C12 NBD Phytoceramide
    C12 NBD Phytoceramide, a ceramide analogue, is a fluorescent substrate, can be used to detect ceramidase activity.
    C12 NBD Phytoceramide
  • HY-159696C
    FAM labled ISIS 449884 sodium
    FAM labled ISIS 449884 sodiumis a FAM labled ISIS 449884 sodium.
    FAM labled ISIS 449884 sodium
  • HY-D0239
    4-Nitro-m-phenylenediamine
    4-Nitro-m-phenylenediamine is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
    4-Nitro-m-phenylenediamine
  • HY-D2169
    AF 568 carboxylic acid
    AF 568 carboxylic acid is the non-reactive form of the orange fluorescent dye AF 568. AF 568 has an absorption wavelength of 590-720 nm (FRET) and an emission wavelength of 515-720 nm. AF 568 alkyne forms stable covalent bonds by reacting carboxylic acid groups with molecules bearing amino groups. Copper-catalyzed azide-alkyne cycloaddition (CuAAc) can occur with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
    AF 568 carboxylic acid
  • HY-124254
    C.I. Vat Yellow 2
    C.I. Vat Yellow 2 is an agent of yellow dye and can also be used for the paper dyeing.
    C.I. Vat Yellow 2
  • HY-112114
    DTPA-DAB2
    DAB2-DTPA is a conjugate of DTPA with two DAB used in the photooxidation experiments.
    DTPA-DAB2
Cat. No. Product Name / Synonyms Application Reactivity