Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Inhibitors (4)

Isotope-Labeled Compounds Related Products (10876):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-W715121S

2,3,7,8-Tetrabromo dibenzo-p-dioxin-¹³C₁₂
2,3,7,8-Tetrabromo dibenzo-p-dioxin-¹³C₁₂ is ¹³C labeled 2,3,7,8-Tetrabromodibenzo[b,E][1,4]dioxine.

HY-100807S1

Quinolinic acid-¹³C₇
Quinolinic acid-¹³C₇ is the ¹³C labeled Quinolinic acid (HY-100807). Quinolinic acid, an endogenous metabolite of tryptophan, is a N-methyl-D-aspartate receptor (NMDA receptor) agonist. Quinolinic acid increases glutamate efflux, induces the generation of ROS, activates nitric oxide synthase, produces excessive NO, leading to calcium ion influx and neuronal apoptosis.

HY-16106S1

Talazoparib-d4
Talazoparib-d₄ (BMN-673-d₄) is deuterium labeled Talazoparib. Talazoparib (BMN-673) is a highly potent, orally active PARP1/2 inhibitor.Talazoparib inhibits PARP1 and PARP2 enzyme activity with K_is of 1.2 nM and 0.87 nM, respectively. Talazoparib has antitumor activity.

HY-W010450S5

Thymine-¹³C₅,¹⁵N,¹⁵N₂
Thymine-¹³C₅,¹⁵N₂ (5-Methyluacil-¹³C₅,¹⁵N₂) is ¹³C and ¹⁵N labeled Thymine. Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-fluorouracil (5-FU) in cancer treatment, with a K_m of 2.3 μM.

HY-132362S

1-(6-Hydroxy-2-propylheptyl) hydrogen 1,2-benzenedicarboxylate-d₄
Monopropylheptylphthalate 6-hydroxy-d4 is the deuterium labeled Monopropylheptylphthalate 6-hydroxy.

HY-173101S

GHFP(Leu-¹³C₆,¹⁵N)AER TFA
GHFP(Leu-¹³C₆,¹⁵N)AER TFA is the ¹³C- and ¹⁵N-labeled GHFP(Leu)AER TFA.

HY-W012578S1

2-Isopropyl-3-methoxypyrazine-¹³C₃
2-Isopropyl-3-methoxypyrazine-¹³C₃ is ¹³C labeled 2-Isopropyl-3-methoxypyrazine.

HY-B0806AS

Proguanil-d₄ hydrochloride
Proguanil-d₄ (hydrochloride) is the deuterium labeled Proguanil hydrochloride. Proguanil hydrochloride, an antimalarial proagent, is metabolized to the active metabolite Cycloguanil (HY-12784). Proguanil hydrochloride is a dihydrofolate reductase (DHFR) inhibitor.

HY-156326S1

(3E,5Z)-Octadien-2-one-¹³C₂
(3E,5Z)-Octadien-2-one-¹³C₂ is ¹³C labeled (3E,5Z)-Octadien-2-one.

HY-W719560S

Flupyrsulfuron-methyl-d₆
Flupyrsulfuron-methyl-d₆ is deuterium labeled Methyl 2-(N-((4,6-dimethoxypyrimidin-2-yl)carbamoyl)sulfamoyl)-6-(trifluoromethyl)nicotinate.

HY-146926S

16:0 Coenzyme A-d₄		99.9%
16:0 Coenzyme A-d₄ is deuterium labeled 16:0 Coenzyme A.

HY-W014888S

Benzy(phenyl)sulfane-d₂
Benzy(phenyl)sulfane-d2 (Benzyl phenyl sylphide-d2) is the deuterium labeled Benzyl(phenyl)sulfane (HY-W014888).

HY-14877S1

Anagliptin-d₇
Anagliptin-d₇ (SK-0403-d₇) is deuterium labeled Anagliptin. Anagliptin (SK-0403) is a highly selective, potent, orally active inhibitor of dipeptidyl peptidase 4 (DPP-4), with an IC₅₀ of 3.8 nM, and less selective at DPP-8 and DDP-9 with IC₅₀s of 68 nM and 60 nM, respectively.

HY-131100S

Homo Sildenafil-d₅
Homo Sildenafil-d₅ is the deuterium labeled Homo Sildenafil. Homo Sildenafil, an analog of Sildenafil, acts as a phosphodiesterase inhibitor.

HY-W020691S

Lactide-d₆
Lactide-d₆ is a deuterium labeled Lactide.

HY-B0152S3

Adenine-¹³C₅
Adenine-¹³C₅ (6-Aminopurine-¹³C₅; Vitamin B4-¹³C₅) is ¹³C-labeled Adenine (HY-B0152). Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis.

HY-W1122690

Vitamin K-d₇
Vitamin K-d₇ is the deuterium labeled Vitamin K (HY-B2172). Vitamin K, the blood-clotting vitamin, is important for the function of numerous proteins within the body, such as the coagulation factors, osteocalcin and matrix-Gla protein.

HY-W010950S

Flecainide-d₃		99.9%
Flecainide-d₃ is the deuterium labeled Flecainide. Flecainide is an orally active antiarrhythmic agent. Flecainide can block sodium channels and inhibit calcium ion release mediated by the cardiac ryanodine receptor (RyR2). Flecainide can be used in the research of diseases such as catecholaminergic polymorphic ventricular tachycardia (CPVT).

HY-165637S

(±)11(12)-DiHET-d₁₁
(±)11(12)-DiHET-d₁₁ is deuterium labeled (±)11(12)-DiHET.

HY-W377440

2-(Methyl-d₃)phenol
2-(Methyl-d₃)phenol is the deuterium labeled 2-(Methyl)phenol.

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