Phosphoglycerate Kinase (PGK) Activator
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AT-051/43421517
0 ImagesAT-051/43421517 is a PGK1 activator with a Kd of 2.45 μM. AT-051/43421517 induces enhanced glycolytic metabolism and maintains TCA cycle activity, while inhibiting ROS production and Apoptosis. AT-051/43421517 reduces Aβ deposition and Tau hyperphosphorylation. AT-051/43421517 alleviates neuropathological damage in the brains of 3×Tg-AD mice. AT-051/43421517 improves cognitive impairment. AT-051/43421517 can be used for research on Alzheimer's disease and Parkinson's disease.
