(S)-Dolaphenine hydrochloride
Based on 1 Customer Validation
(S)-Dolaphenine hydrochloride is a component of Dolastatin 10 (HY-15580). Dolastatin 10, an antineoplastic agent, inhibits tubulin polymerization.
For research use only. We do not sell to patients.
- Purity: 98.54%
- CAS No.: 135383-60-7
- Formula: C11H13ClN2S
- Molecular Weight:240.75
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
Chemical Information
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CAS No. 135383-60-7
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Appearance Solid
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Molecular Weight 240.75
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Formula C11H13ClN2S
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Color Light yellow to yellow
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SMILES
N[C@H](C1=NC=CS1)CC2=CC=CC=C2.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : ≥ 50 mg/mL (207.68 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : ≥ 50 mg/mL (207.68 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO / H2O | 1 mM | 4.1537 mL | 20.7684 mL | 41.5369 mL | 103.8422 mL |
| 5 mM | 0.8307 mL | 4.1537 mL | 8.3074 mL | 20.7684 mL | |
| 10 mM | 0.4154 mL | 2.0768 mL | 4.1537 mL | 10.3842 mL | |
| 15 mM | 0.2769 mL | 1.3846 mL | 2.7691 mL | 6.9228 mL | |
| 20 mM | 0.2077 mL | 1.0384 mL | 2.0768 mL | 5.1921 mL | |
| 25 mM | 0.1661 mL | 0.8307 mL | 1.6615 mL | 4.1537 mL | |
| 30 mM | 0.1385 mL | 0.6923 mL | 1.3846 mL | 3.4614 mL | |
| 40 mM | 0.1038 mL | 0.5192 mL | 1.0384 mL | 2.5961 mL | |
| 50 mM | 0.0831 mL | 0.4154 mL | 0.8307 mL | 2.0768 mL | |
| 60 mM | 0.0692 mL | 0.3461 mL | 0.6923 mL | 1.7307 mL | |
| 80 mM | 0.0519 mL | 0.2596 mL | 0.5192 mL | 1.2980 mL | |
| 100 mM | 0.0415 mL | 0.2077 mL | 0.4154 mL | 1.0384 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.