1. Anti-infection
  2. Bacterial
  3. Amycolatopsin A

Amycolatopsin A is a 20-membered macrolide, that can be isolated from a strain of the rare actinomycete Amycolatopsis sp. MST‐108494. Amycolatopsin A shows antimycobacterial activity against Mycobacterium bovis (BCG) and M. tuberculosis (H37Rv) with IC50 values of 0.4 µM and 4.4 µM, respectively.

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Amycolatopsin A

Amycolatopsin A 화학구조

CAS No. : 2209112-96-7

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제품 설명

Amycolatopsin A is a 20-membered macrolide, that can be isolated from a strain of the rare actinomycete Amycolatopsis sp. MST‐108494. Amycolatopsin A shows antimycobacterial activity against Mycobacterium bovis (BCG) and M. tuberculosis (H37Rv) with IC50 values of 0.4 µM and 4.4 µM, respectively[1].

In Vitro

Amycolatopsin A displays significant cytotoxicity against human colon carcinoma (SW620) and lung carcinoma (NCIH-460) cell lines with IC50 values of 0.08 µM and 1.2 µM, respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

분자량

1187.41

화학식

C60H98O23

CAS No.
SMILES

C[C@]1([C@H](O[C@](O)([C@@H]([C@H]1O)OC)[C@@H](C2([H])CC(C(/C=C(/C=C(/C=C(C(C(/C=C(/C=C(\C=C(C(O2)=O)/C)OC)CO)C)O[C@@H]3[C@@H]([C@H]([C@@H]([C@H](O3)C)OC)O)O)/C)C)C)O)OC)C)CCCOC)O[C@H]4C[C@@H]([C@@H]([C@H](O4)C)O[C@H]5C[C@@](O)([C@@H]([C@H](O5)C)O)C)O

Structure Classification
Initial Source

Amycolatopsis sp.

선적

Room temperature in continental US; may vary elsewhere.

보관

Please store the product under the recommended conditions in the Certificate of Analysis.

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상품명:
Amycolatopsin A
Cat. No.:
HY-N11048
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