2. Productos naturales
  3. Disease Research Fields Plants Steroids
  4. Liliaceae Cardiovascular Disease
  5. Anemarrhena asphodeloides Bunge
  6. Anemarrhenasaponin A2

Anemarrhenasaponin A2  (Synonyms: Schidigerasaponin F2; Timosaponin AII)

Cat. No.: HY-N7614 Pureza: 95.38%
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Anemarrhenasaponin A2 (Schidigerasaponin F2) is a steroidal saponin isolated from the rhizomes of Anemarrhena asphodeloides. Anemarrhenasaponin A2 inhibits ADP-induced platelet aggregation.

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Anemarrhenasaponin A2

Anemarrhenasaponin A2 Estructura química

No. CAS : 117210-12-5

Tamaño Precio Stock Cantidad
1 mg En stock
5 mg En stock
10 mg En stock
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100 mg   Obtener un presupuesto  

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Based on 1 publication(s) in Google Scholar

Anemarrhenasaponin A2 Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE Anemarrhenasaponin A2

  • Actividad biológica

  • Pureza y Documentación

  • Referencias

  • Revisión del cliente

Descripciòn

Anemarrhenasaponin A2 (Schidigerasaponin F2) is a steroidal saponin isolated from the rhizomes of Anemarrhena asphodeloides. Anemarrhenasaponin A2 inhibits ADP-induced platelet aggregation[1].

Peso molecular

756.92

Fòrmula

C39H64O14
No. CAS
Appearance

Solid

Color

White to off-white

SMILES

C[C@@]12[C@]([C@@H]3C)([H])[C@](O[C@]3(OC4)CC[C@@H]4C)([H])C[C@@]1([H])[C@@](CC[C@@](C[C@H]5O[C@H](O[C@@H]6CO)[C@@H]([C@H]([C@H]6O)O)O[C@@H]([C@@H]([C@H]7O)O)O[C@@H]([C@H]7O)CO)([H])[C@@]8(C[C@@H]5O)C)([H])[C@]8([H])CC2
Structure Classification
Initial Source
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvente y solubilidad
In Vitro: 

DMSO : ≥ 100 mg/mL (132.11 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.3211 mL 6.6057 mL 13.2114 mL
5 mM 0.2642 mL 1.3211 mL 2.6423 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Calculadora de molaridad

  • Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in Saline)

    Solubility: ≥ 2.5 mg/mL (3.30 mM); Clear solution

    This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).

    Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.

    Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
%
DMSO +
% 
+
%
Tween-80 +
%
Saline
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Calculation results:
Working solution concentration: mg/mL
Method for preparing stock solution: mg drug dissolved in μL  DMSO (Stock solution concentration: mg/mL).

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).
Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.
 If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Pureza y Documentación
Referencias

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.3211 mL 6.6057 mL 13.2114 mL 33.0286 mL
5 mM 0.2642 mL 1.3211 mL 2.6423 mL 6.6057 mL
10 mM 0.1321 mL 0.6606 mL 1.3211 mL 3.3029 mL
15 mM 0.0881 mL 0.4404 mL 0.8808 mL 2.2019 mL
20 mM 0.0661 mL 0.3303 mL 0.6606 mL 1.6514 mL
25 mM 0.0528 mL 0.2642 mL 0.5285 mL 1.3211 mL
30 mM 0.0440 mL 0.2202 mL 0.4404 mL 1.1010 mL
40 mM 0.0330 mL 0.1651 mL 0.3303 mL 0.8257 mL
50 mM 0.0264 mL 0.1321 mL 0.2642 mL 0.6606 mL
60 mM 0.0220 mL 0.1101 mL 0.2202 mL 0.5505 mL
80 mM 0.0165 mL 0.0826 mL 0.1651 mL 0.4129 mL
100 mM 0.0132 mL 0.0661 mL 0.1321 mL 0.3303 mL
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Anemarrhenasaponin A2 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anemarrhenasaponin A2117210-12-5Schidigerasaponin F2 Timosaponin AIIAnemarrhenasaponin A 2Anemarrhenasaponin A-2Schidigerasaponin F 2Schidigerasaponin F-2OthersADPsteroidalsaponinplateletaggregatioInhibitorinhibitorinhibit

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Nombre del producto:
Anemarrhenasaponin A2
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HY-N7614
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