Anti-osteoporosis agent-10
Anti-osteoporosis agent-10 is an osteoporosis inhibitor. Anti-osteoporosis agent-10 can suppress the generation of osteoclasts, with an IC50 of 0.042 μM. Anti-osteoporosis agent-10 also has antagonistic activity on PPARγ, with an EC50 value of 0.75 μM.
For research use only. We do not sell to patients.
- Formula: C27H31F3O6
- Molecular Weight:508.53
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| BMDM | IC50 |
0.042 μM
Compound: 34
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Inhibition of osteoclastogenesis in C57BL/6J mouse Bone marrow macrophage cells assessed as inhibition of RANKL-stimulated osteoclast formation measured after 6 days by tartrate-resistant acid phosphatase (TRAP) staining assay
Inhibition of osteoclastogenesis in C57BL/6J mouse Bone marrow macrophage cells assessed as inhibition of RANKL-stimulated osteoclast formation measured after 6 days by tartrate-resistant acid phosphatase (TRAP) staining assay
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[PMID: 39185622] |
Chemical Information
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Molecular Weight 508.53
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Formula C27H31F3O6
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SMILES
O=C1OCC(CC[C@]2([C@@H](C[C@@H]([C@]3(C(CCC[C@@]32[H])=O)COC(C4=CC=C(C=C4)C(F)(F)F)=O)O)C)C)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Anti-osteoporosis agent-10 Related Classifications
HY-169070 Related Classifications
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