ACOX1 Antibody (YA1979)(PBS only)

Cat. No.: HY-P82234A: Data Sheet User Guide for Antibodies
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ACOX1 Antibody (YA1979) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ACOX1.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

ACOX1 Antibody (YA1979) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ACOX1.

Host

Rabbit

Molecular Weight

Predicted band size: 75 kDa;

Observed band size: 74,48 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q9R0H0

Gene ID

51 [NCBI]

Immunogen

Recombinant protein of mouse ACOX1 aa1-270.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:50-1:200
IP IP: Immunoprecipitation	1:20

Purity	Affinity Purified	Conjugation	Non-conjugated
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Involved in the initial and rate-limiting step of peroxisomal beta-oxidation of straight-chain saturated and unsaturated very-long-chain fatty acids. Catalyzes the desaturation of fatty acyl-CoAs such as palmitoyl-CoA (hexadecanoyl-CoA) to 2-trans-enoyl-CoAs ((2E)-enoyl-CoAs) such as (2E)-hexadecenoyl-CoA, and donates electrons directly to molecular oxygen (O(2)), thereby producing hydrogen peroxide (H(2)O(2)); Shows highest activity against medium-chain fatty acyl-CoAs. Shows optimum activity with a chain lengtH2O2 10 carbons (decanoyl-CoA) in vitro; Is active against a much broader range of substrates and shows activity towards long-chain acyl-CoAs

Subcellular Localization：Peroxisome

Expression：
Tissue_specificity:Highest levels of isoform 1 are found in liver and kidney while highest levels of isoform 2 are found in white adipose tissue. Isoform 1 is expressed at higher levels than isoform 2 in liver and kidney while isoform 2 is expressed at higher levels in brain, heart, lung, muscle, white adipose tissue and testis

Isoforms & Post-Translational Modification：Q9R0H0 has 2 isomers: Q9R0H0-1: 74649 Da (predicted); Q9R0H0-2: 74718 Da (predicted).

Subunit：Homodimer (By similarity). Interacts with LONP2 (By similarity)

Research Field

Signal Transduction

Synonyms

AOX; Acox; Paox; D130055E20Rik

Documentation

User Guide for Antibodies (1077 KB)