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Anterior Gradient 2 Antibody (YA3577)

(Synonyms: AG2; GOB-4; HAG-2; XAG-2; PDIA17; HEL-S-116)
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Anterior Gradient 2 Antibody (YA3577) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Anterior Gradient 2.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG1

  • Application:

    ICC/IF, FC, ELISA

  • Reactivity :

    Human

  • Formulation:

    Supplied in PBS with 0.05% sodium azide

  • Conjugation:
    Non-conjugated
  • Anterior Gradient 2 Antibody (YA3577) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
ICC/IF Info
ICC/IF: Immunocytochemistry/
Immunofluorescence
FC Info
FC: Flow Cytometry
ELISA Info
ELISA: Enzyme Linked Immunosorbent Assay
Dilution Ratio 1:200-1:1000 1:200-1:400 1:10000

Product Details

Description

Anterior Gradient 2 Antibody (YA3577) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Anterior Gradient 2.

  • Host Mouse
  • Clonality Monoclonal
  • Species Reactivity
    Human
  • Observed Molecular Weight
    Observed band size: 20 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 20 kDa
Immunogen

Purified recombinant fragment of human AGR2 (AA: 21-175) expressed in E. Coli.

Purification

affinity purified.

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG1

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS with 0.05% sodium azide

  • Concentration

    Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    Anterior Gradient 2 is required for MUC2 post-transcriptional synthesis and secretion. May play a role in the production of mucus by intestinal cells. Proto-oncogene that may play a role in cell migration, cell differentiation and cell growth. Promotes cell adhesion[1].

  • Subcellular Localization

    Secreted; Endoplasmic reticulum

  • Expression


    Tissue_specificity:It is highly expressed in the trachea, lungs, stomach, colon, prostate, and small intestine. It is lowly expressed in the pituitary gland, salivary glands, mammary glands, bladder, appendix, ovary, fetal lungs, uterus, pancreas, kidneys, fetal kidneys, testes, placenta, thyroid gland, and estrogen receptor (ER) positive breast cancer cell lines.

  • Subunit

    Monomer and homodimer (PubMed:23274113). Interacts with LYPD3 and DAG1 (alphaDAG1) (PubMed:12592373). Interacts with MUC2; disulfide-linked (PubMed:19359471, PubMed:34237462)

  • SwissProt ID

    O95994

  • Gene ID
    10551 [NCBI]
  • Synonyms

    AG2; GOB-4; HAG-2; XAG-2; PDIA17; HEL-S-116

Anterior Gradient 2 Antibody (YA3577) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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    1/16
  • Anterior Gradient 2 Antibody (YA3577) Product Image