ASGR2 Antibody (YA3684)
(Synonyms: HL-2; HBXBP; ASGPR2; ASGP-R2; CLEC4H2)
Based on 1 Customer Validation
ASGR2 Antibody (YA3684) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to ASGR2.
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Host:
Mouse
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Isotype:
IgG1
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Application:
IHC-P, FC, ELISA
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Reactivity :
Human
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Formulation:
Supplied in PBS with 0.05% sodium azide
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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FC
FC: Flow Cytometry
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ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|---|
| Dilution Ratio | 1:200-1:1000 | 1:200-1:400 | 1:10000 |
Product Details
ASGR2 Antibody (YA3684) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to ASGR2.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 35 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 35 kDa
Purified recombinant fragment of human ASGR2 (AA: 80-311) expressed in E. Coli.
affinity purified.
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS with 0.05% sodium azide
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Concentration
Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
ASGR2 mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface
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Subcellular Localization
Membrane; Single-pass type II membrane protein
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Expression
Tissue_specificity:Expressed exclusively in hepatic parenchymal cells -
Isoforms & Post-Translational Modification
P07307 has 3 isomers: P07307-1: 35092 Da (predicted); P07307-2: 32988 Da (predicted); P07307-3: 32550 Da (predicted).
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Subunit
The functioning ligand-binding unit of this receptor is thought to be at least a dimer. Interacts with LASS2
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SwissProt ID
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Synonyms
HL-2; HBXBP; ASGPR2; ASGP-R2; CLEC4H2
Documentation
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