CD269/BCMA Antibody (YA1501)
(Synonyms: TNFRSF17; BCM; BCMA; Tumor necrosis factor receptor superfamily member 17; B-cell maturation protein; CD269)CD269/BCMA Antibody (YA1501) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD269/BCMA.
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Host:
Rabbit
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Isotype:
IgG
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Application:
ICC/IF, FC, IP, ELISA
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Reactivity :
Human
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Formulation:
Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
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Conjugation:
Non-conjugated
Applications
| Application |
FC
FC: Flow Cytometry
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ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|---|
| Dilution Ratio | 1:50-1:100 | 1:10000 | 1:50-1:200 |
Product Details
CD269/BCMA Antibody (YA1501) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD269/BCMA.
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Host Rabbit
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Clonality Recombinant,Monoclonal
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 20 kDaNote: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 20 kDa
Recombinant human BCMA protein
Endogenous
Affinity Chromatography
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
CD269/BCMA receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK
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Subcellular Localization
Cell membrane; Single-pass type III membrane protein; Endomembrane system; Single-pass type III membrane protein
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Expression
Tissue_specificity:It is expressed in mature B cells, but not in T cells or monocytes. -
Isoforms & Post-Translational Modification
Q02223 has 2 isomers: Q02223-1: 20165 Da (predicted); Q02223-2: 14843 Da (predicted).
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Subunit
Associates with TRAF1, TRAF2, TRAF3, TRAF5 and TRAF6
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SwissProt ID
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Synonyms
TNFRSF17; BCM; BCMA; Tumor necrosis factor receptor superfamily member 17; B-cell maturation protein; CD269
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Research Field
Signal Transduction
Documentation