2. Antibodies
  3. Primary Antibodies
  4. Recombinant Antibodies
  5. Calpain 2 Antibody (YA572)

Calpain 2 Antibody (YA572)

Cat. No.: HY-P80444
User Guide for Antibodies Technical Support

Calpain 2 Antibody (YA572) is a Rabbit-derived and non-conjugated IgG recombinant monoclonal antibody, targeting to Calpain 2.

For research use only. We do not sell to patients.

Size Price Stock Quantity
20 μL Get quote 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
50 μL Get quote 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
100 μL Get quote 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
250 μL   Get quote  
Synthetic products have potential research and development risk.
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Top Publications Citing Use of Products

1 Publications Citing Use of MCE Calpain 2 Antibody (YA572)

  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

  • Product Detail

  • Background

  • Documentation

Description

Calpain 2 Antibody (YA572) is a Rabbit-derived and non-conjugated IgG recombinant monoclonal antibody, targeting to Calpain 2.
Host

Rabbit
Clonality

Monoclonal,Recombinant
Molecular Weight
Predicted band size: 80kDa;
Observed band size: 80kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Species Reactivity
Human
SwissProt ID
Gene ID
Immunogen

A synthesized peptide derived from human CAPN2. The exact sequence is proprietary to MCE.
Application &
Dilution Ratio
Application Dilution Ratio
WB
WB: Western Blot
1:500-2000
ICC/IF
ICC/IF: Immunocytochemistry/Immunofluorescence
1:50-200
IHC-P
IHC-P: Immunohistochemistry-Paraffin
1:50-200
FC
FC: Flow Cytometry
1:50
Sensitivity Endogenous Purity affinity purified by Protein A
Conjugation Non-conjugated Modification Unmodified
Isotype IgG  
Appearance

Liquid
Formulation

Supplied in10mM TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.
Background
Function：Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226' (PubMed:17650508). Proteolytically cleaves CPEB3 following neuronal stimulation which abolishes CPEB3 translational repressor activity, leading to translation of CPEB3 target mRNAs (By similarity)
Subcellular Localization：Cytoplasm; Cell membrane
Expression：
Tissue_specificity:Ubiquitous
Subunit：Forms a heterodimer with a small (regulatory) subunit (CAPNS1). Interacts with PIDD1 alternative open reading frame protein altPIDD1 (PubMed:39532532)
Database

Entrez Gene: 824 Human ; 29154 Rat

SwissProt: P17655 Human ; Q07009 Rat

OMIM: 114230 Human

Documentation
User Guide for Antibodies (1077 KB)

Calpain 2 Antibody (YA572) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Calpain 2 Antibody (YA572)
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HY-P80444
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