cbx7 Antibody (YA6845)
(Synonyms: Cbx 7 antibody; CBX7 antibody; Chromobox homolog 7 antibody; Chromobox protein homolog 7 antibody; )cbx7 Antibody (YA6845) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to cbx7.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, FC
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Reactivity :
Human
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Formulation:
Supplied in 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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FC
FC: Flow Cytometry
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|---|---|---|
| Dilution Ratio | 1:500-1:2000 | 1:50-1:100 |
Product Details
cbx7 Antibody (YA6845) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to cbx7.
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Host Rabbit
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Clonality Recombinant,Monoclonal
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Species ReactivityHuman
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Calculated Molecular Weight Predicted band size: 28 kDa
Recombinant protein within Human cbx7 aa 1-190 / 251.
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
cbx7 component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Promotes histone H3 trimethylation at 'Lys-9' (H3K9me3). Binds to trimethylated lysine residues in histones, and possibly also other proteins. Regulator of cellular lifespan by maintaining the repression of CDKN2A, but not by inducing telomerase activity
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Subcellular Localization
Nucleus
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Isoforms & Post-Translational Modification
O95931: 251 amino acids, molecular weight 28341 Da.
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Subunit
Component of a PRC1-like complex
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SwissProt ID
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Synonyms
Cbx 7 antibody; CBX7 antibody; Chromobox homolog 7 antibody; Chromobox protein homolog 7 antibody;
Documentation
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