2. Gene
  3. CBX7 - chromobox 7 Gene

CBX7 - chromobox 7 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens
Gene ID: 23492 | Gene type: protein coding

About CBX7

Cytogenetic location: 22q13.1 Genomic coordinates (GRCh38): 22:39,130,772-39,152,680 (from NCBI)

This gene has 7 transcripts (splice variants), 269 orthologues and 8 paralogues. Ubiquitous expression in ovary (RPKM 27.3), endometrium (RPKM 25.8) and 25 other tissues.

Summary

This gene encodes a protein that contains the CHROMO (CHRomatin Organization MOdifier) domain. The encoded protein is a component of the Polycomb repressive complex 1 (PRC1), and is thought to control the lifespan of several normal human cells. [provided by RefSeq, Oct 2016]

CBX7 Products(3)

mRNA Protein Name
NM_001346743.2 NP_001333672.1 chromobox protein homolog 7 isoform 2
NM_001346744.2 NP_001333673.1 chromobox protein homolog 7 isoform 3
NM_175709.5 NP_783640.1 chromobox protein homolog 7 isoform 1

CBX7 Protein Structure

Chromo

Chromo: Chromo (CHRromatin Organisation MOdifier) domain (11 - 60)

  • 0
  • 100
  • 200
  • 251 a.a.
Protein Preferred Names Protein Names

chromobox protein homolog 7

Related Diseases

Diseases Alias
Ovarian Clear Cell Adenocarcinoma
Klippel-Feil Syndrome 4
Melanoma, Cutaneous Malignant 1

Familial Melanoma

Melanoma, Cutaneous Malignant, Susceptibility To, 1

Melanoma, Malignant

CMM1

Melanoma, Cutaneous Malignant

Cmm

Familial Atypical Mole-Malignant Melanoma Syndrome

Fammm

Melanoma, Familial

Mlm

Dysplastic Nevus Syndrome, Hereditary

Dns

B-K Mole Syndrome

Melanoma, Cutaneous Malignant, 1

Malignant Melanoma, Cutaneous

Melanoma, Cutaneous, Malignant, Susceptibility To, Type 1

Dysplastic Nevus Syndrome

Cutaneous Melanoma

Familial Atypical Mole Melanoma Syndrome

Hereditary Melanoma
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-100832 UNC3866 Inhibitor 97.14% Unkown
HY-119344 MS37452 Inhibitor 99.22% Unkown
HY-126327 UNC4976 Antagonist / Unkown
HY-126327A UNC4976 TFA Antagonist ≥98.0% Unkown
HY-RS02014 CBX7 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus CBX7 RGD RGD:735027
Macaca mulatta CBX7 VGNC VGNC:70561
Felis catus CBX7 VGNC VGNC:60425
Canis familiaris CBX7 VGNC VGNC:38768
Bos taurus CBX7 VGNC VGNC:26820
Mus musculus CBX7 MGD MGI:1196439